Congenital leptin deficiency is associated with severe early-onset obesity in humans
- Author
- MONTAGUE, C. T1 ; FAROOQI, I. S1 2 ; CHEETHAM, C. H6 ; EARLEY, A. R6 ; BARNETT, A. H7 ; PRINS, J. B1 2 ; O'RAHILLY, S1 2 ; WHITEHEAD, J. P1 2 ; SOOS, M. A1 2 ; RAU, H1 2 ; WAREHAM, N. J3 ; SEWTER, C. P1 2 ; DIGBY, J. E1 2 ; MOHAMMED, S. N4 ; HURST, J. A5
[1] University of Cambridge, Department of Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QR, United Kingdom
[2] University of Cambridge, Department of Clinical Biochemistry, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QR, United Kingdom
[3] University of Cambridge, Department of Community Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QR, United Kingdom
[4] South Thames Regional Genetics Centre (East), Guy's Hospital, London SE1 9RT, United Kingdom
[5] Oxford Regional Genetics Service, Churchill Hospital, Oxford OX3 7LJ, United Kingdom
[6] Wycombe General Hospital, Queen Alexandra Road, High Wycombe, Buckinghamshire HP11 2TT, United Kingdom
[7] Department of Medicine, University of Birmingham and Birmingham Heartlands Hospital, Birmingham B9 5SS, United Kingdom - Source
Nature (London). 1997, Vol 387, Num 6636, pp 903-908 ; ref : 21 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Bilan énergétique Etat nutritionnel Etiopathogénie Homme Mutation Obésité Leptine Trouble nutrition
- Keyword (en)
- Energy balance Nutritional status Etiopathogenesis Human Mutation Obesity Leptin Nutrition disorder
- Keyword (es)
- Balance energético Estado nutricional Etiopatogenia Hombre Mutación Obesidad Trastorno nutricíon
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Discipline
- Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2701538
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/43185 
https://dx.doi.org/10.1038/43185
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