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The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin

Author
D'ANGELO, Daniela1 ; BORBONE, Eleonora1 4 ; PALMIERI, Dario1 ; UBOLDI, Sarah2 ; ESPOSITO, Francesco1 ; FRAPOLLI, Roberta2 ; PACELLI, Roberto3 ; D'INCALCI, Maurizio2 ; FUSCO, Alfredo1 4
[1] Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, Naples, Italy
[2] Department of Oncology, Mario Negri Institute for Pharmacological Research, Milan, Italy
[3] Istituto di Biostrutture e Bioimmagini del CNR, Naples, Italy
[4] NOGEC (Naples Oncogenomic Center), CEINGE-Biotecnologie Avanzate, Napoli, and SEMM - European School of Molecular Medicine ― Naples Site, Naples, Italy
Source

European journal of cancer (1990). 2013, Vol 49, Num 5, pp 1142-1151, 10 p ; ref : 35 ref

ISSN
0959-8049
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Cancer Chromatin HMGA Trabectedin
Keyword (fr)
Activité biologique Anticancéreux Cancer Cancérologie Chromatine Mobilité Protéine A Trabectédine Tumeur maligne Ectéinascidine 743
Keyword (en)
Biological activity Antineoplastic agent Cancer Cancerology Chromatin Mobility Protein A Trabectedin Malignant tumor
Keyword (es)
Actividad biológica Anticanceroso Cáncer Cancerología Cromatina Movilidad Proteína A Trabectedina Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
General pharmacology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
27165458

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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