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Gene expression changes associated with erlotinib response in glioma cell lines

Author
GARCIA-CLAVER, Ainoha1 ; LORENTE, Mar2 ; MUR, Pilar1 ; CAMPOS-MARTIN, Yolanda1 ; MOLLEJO, Manuela1 3 ; VELASCO, Guillermo2 ; MELENDEZ, Barbara1
[1] Molecular Pathology Research Unit, Virgen de la Salud Hospital, Toledo, Spain
[2] Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University and Instituto de Investigación Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain
[3] Department of Pathology, Virgen de la Salud Hospital, Toledo, Spain
Source

European journal of cancer (1990). 2013, Vol 49, Num 7, pp 1641-1653, 13 p ; ref : 38 ref

ISSN
0959-8049
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Epidermal growth factor receptor Erlotinib Glioblastoma multiforme Glioma cell lines Gliomas MAPK/Erk pathway Microarray expression assays PI3K/Akt pathway PTEN Temsirolimus
Keyword (fr)
1-Phosphatidylinositol 3-kinase Akt protein kinase Anticancéreux Association Cancérologie Changement Dosage Erlotinib Expression génique Extracellular signal-regulated protein kinase Glioblastome multiforme Gène PTEN Gène suppresseur tumeur Immunodépresseur Lignée cellulaire établie Lignée cellulaire Mitogen-activated protein kinase Récepteur facteur croissance épiderme Récepteur facteur croissance Temsirolimus Anti-EGFR Inhibiteur de la tyrosine kinase de l'EGFR Inhibiteur mTOR Cancer Dérivé de la quinazoline Enzyme Gliome malin Inhibiteur de la tyrosine kinase Inhibiteur enzyme Pathologie du système nerveux central Pathologie du système nerveux Protein-tyrosine kinase Transferases Tumeur maligne
Keyword (en)
1-Phosphatidylinositol 3-kinase Akt protein kinase Antineoplastic agent Association Cancerology Change Assay Erlotinib Gene expression Extracellular signal-regulated protein kinase Glioblastoma multiforme PTEN Gene Tumor suppressor gene Immunosuppressive agent Established cell line Cell line Mitogen-activated protein kinase Epidermal growth factor receptor Growth factor receptor Temsirolimus Cancer Quinazoline derivatives Enzyme Malignant glioma Tyrosine kinase inhibitor Enzyme inhibitor Central nervous system disease Nervous system diseases Protein-tyrosine kinase Transferases Malignant tumor
Keyword (es)
1-Phosphatidylinositol 3-kinase Akt protein kinase Anticanceroso Asociación Cancerología Cambio Dosificación Erlotinib Expresión genética Extracellular signal-regulated protein kinase Glioblastoma multiforme Gen PTEN Gen supresor tumor Inmunodepresor Línea celular establecida Línea celular Mitogen-activated protein kinase Receptor del factor de crecimiento epidérmico Receptor factor crecimiento Temsirolimus Cáncer Enzima Glioma maligno Inhibidor tyrosine kinase Inhibidor enzima Sistema nervosio central patología Sistema nervioso patología Protein-tyrosine kinase Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)

Discipline
General pharmacology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
27302381

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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