Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases
- Author
- LAHIRI, Sushmita D1 ; MANGANI, Stefano2 ; DURAND-REVILLE, Thomas3 ; BENVENUTI, Manuela2 ; DE LUCA, Filomena4 ; SANYAL, Gautam1 ; DOCQUIER, Jean-Denis4
[1] Infection Biosciences, AstraZeneca R&D Boston, Waltham, Massachusetts, United States
[2] Dipartimento di Chimica, Università degli Studi di Siena, Siena, Italy
[3] Infection Chemistry, AstraZeneca R&D Boston, Waltham, Massachusetts, United States
[4] Dipartimento di Biotecnologie Mediche, Università degli Studi di Siena, Siena, Italy - Source
Antimicrobial agents and chemotherapy. 2013, Vol 57, Num 6, pp 2496-2505, 10 p ; ref : 46 ref
- CODEN
- AACHAX
- ISSN
- 0066-4804
- Scientific domain
- Microbiology, infectious diseases; Pharmacology drugs
- Publisher
- American Society for Microbiology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Inhibition Mécanisme action Pseudomonas aeruginosa Spectre β-Lactamase Avibactam Bactérie Enzyme Hydrolases Inhibiteur enzyme Pseudomonadaceae Pseudomonadales
- Keyword (en)
- Inhibition Mechanism of action Pseudomonas aeruginosa Spectrum β-Lactamase Avibactam Bacteria Enzyme Hydrolases Enzyme inhibitor Pseudomonadaceae Pseudomonadales
- Keyword (es)
- Inhibición Mecanismo acción Pseudomonas aeruginosa Espectro β-Lactamase Avibactam Bacteria Enzima Hydrolases Inhibidor enzima Pseudomonadaceae Pseudomonadales
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27423539
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1128/AAC.02247-12 
https://dx.doi.org/10.1128/AAC.02247-12
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