The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
- Author
- SAHM, Felix1 2 3 ; OEZEN, Iris1 3 4 ; PLATTEN, Michael1 3 4 ; OPITZ, Christiane A1 3 4 ; RADLWIMMER, Bernhard5 ; VON DEIMLING, Andreas2 ; AHRENDT, Tilman6 ; ADAMS, Seray7 ; BODE, Helge B6 ; GUILLEMIN, Gilles J7 ; WICK, Wolfgang3 4
[1] Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), University Hospital Heidelberg, Germany
[2] Department of Neuropathology, University Hospital Heidelberg, Germany
[3] Department of Neurooncology, University Hospital Heidelberg, Germany
[4] National Center for Tumor Diseases, German Cancer Research Center (DKFZ), Heidelberg, Germany
[5] Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany
[6] Merck Stiftungsprofessur für Molekulare Biotechnologie, Fachbereich Biowissenschaften, Goethe Universität, Frankfurt, Germany
[7] Australian School of Advanced Medicine, Macquarie University, North Ryde, New South Wales, Australia - Source
Cancer research (Chicago, Ill.). 2013, Vol 73, Num 11, pp 3225-3234, 10 p ; ref : 58 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Endogène Gliome Métabolite Précurseur Résistance Stress oxydatif Tryptophane Aminoacide Pathologie du système nerveux central Pathologie du système nerveux Tumeur
- Keyword (en)
- Endogenous Glioma Metabolite Precursor Resistance Oxidative stress Tryptophan Aminoacid Central nervous system disease Nervous system diseases Tumor
- Keyword (es)
- Endógeno Glioma Metabolito Precursor Resistencia Estrés oxidativo Triptófano Aminoácido Sistema nervosio central patología Sistema nervioso patología Tumor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses
- Discipline
- Neurology Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27448239
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-12-3831 
https://dx.doi.org/10.1158/0008-5472.CAN-12-3831
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