Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients
- Author
- COIT, Patrick1 ; JEFFRIES, Matlock2 ; ALTOROK, Nezam1 ; DOZMOROV, Mikhail G3 ; KOELSCH, Kristi A3 ; WREN, Jonathan D3 4 ; MERRILL, Joan T5 ; MCCUNE, W. Joseph1 ; SAWALHA, Amr H1
[1] Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States
[2] Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States
[3] Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States
[4] Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States
[5] Clinical Pharmacology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States - Source
Journal of autoimmunity (Print). 2013, Vol 43, pp 78-84, 7 p ; ref : 17 ref
- ISSN
- 0896-8411
- Scientific domain
- Immunology, immunopathology, allergology
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- DNA methylation Lupus Methylome Naive CD4+ T cells Type-I interferon
- Keyword (fr)
- Accessibilité Cellule naïve DNA Epigénétique Gène Génome Génétique Homme Immunologie Interféron Lupus érythémateux disséminé Lymphocyte T CD4 Lymphocyte T Méthylation Régulation Transcription Cytokine Immunopathologie Maladie autoimmune Maladie de système Pathologie de la peau Pathologie du tissu conjonctif
- Keyword (en)
- Accessibility Naive cell DNA Epigenetics Gene Genome Genetics Human Immunology Interferon Systemic lupus erythematosus CD4 T lymphocyte T-Lymphocyte Methylation Regulation(control) Transcription Cytokine Immunopathology Autoimmune disease Systemic disease Skin disease Connective tissue disease
- Keyword (es)
- Accesibilidad Célula ingenua DNA Epigenética Gen Genoma Genética Hombre Inmunología Interferón Lupus eritematoso sistémico Linfocito T CD4 Linfocito T Metilación Regulación Transcripción Citoquina Inmunopatología Enfermedad autoinmune Enfermedad sistémica Piel patología Tejido conjuntivo patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B07 Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
- Discipline
- Fundamental immunology Sarcoidosis. Granulomatosis of undetermined origin. Connective tissue diseases. Vasculitides
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27448439
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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