Lack of a Pharmacokinetic Interaction Between Treprostinil Diolamine and Sildenafil in Healthy Adult Volunteers
- Author
- GOTZKOWSKY, S. Karl1 ; KUMAR, Parag1 ; MOTTOLA, David1 ; LALIBERTE, Kevin1
[1] Product Development, United Therapeutics Corporation, Research Triangle Park, NC, United States - Source
Journal of cardiovascular pharmacology. 2013, Vol 61, Num 5, pp 444-451, 8 p ; ref : 23 ref
- CODEN
- JCPCDT
- ISSN
- 0160-2446
- Scientific domain
- Cardiology, blood circulation, phlebology; Pharmacology drugs
- Publisher
- Lippincott, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- pharmacokinetics pulmonary arterial hypertension revatio sildenafil treprostinil
- Keyword (fr)
- Diolamine Homme Hypertension artérielle pulmonaire Individu sain Interaction Pharmacocinétique Sildénafil Tréprostinil Vasodilatateur Prostacycline 3',5'-Cyclic-GMP phosphodiesterase Enzyme Esterases Hydrolases Inhibiteur de la phosphodiesterase Inhibiteur de la phosphodiestérase 5 Inhibiteur enzyme Pathologie de l'appareil circulatoire Pathologie de l'appareil respiratoire Phosphoric diester hydrolases Prostaglandine I2
- Keyword (en)
- Diolamine Human Pulmonary hypertension Healthy subject Interaction Pharmacokinetics Sildenafil Treprostinil Vasodilator agent 3',5'-Cyclic-GMP phosphodiesterase Enzyme Esterases Hydrolases Phosphodiesterase inhibitor Phosphodiesterase 5 inhibitor Enzyme inhibitor Cardiovascular disease Respiratory disease Phosphoric diester hydrolases Prostaglandin I2
- Keyword (es)
- Diolamina Hombre Hipertensión arterial pulmonar Individuo sano Interacción Farmacocinética Sildenafilo Treprostinilo Vasodilatador 3',5'-Cyclic-GMP phosphodiesterase Enzima Esterases Hydrolases Inhibidor phosphodiesterase Inhibidor fosfodiesterasa 5 Inhibidor enzima Aparato circulatorio patología Aparato respiratorio patología Phosphoric diester hydrolases Prostaglandina I2
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11C Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
- Discipline
- Pharmacological treatments Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27450362
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1097/FJC.0b013e3182893d90 
https://dx.doi.org/10.1097/FJC.0b013e3182893d90
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