Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with in-vial derivatization and headspace-trap gas chromatography-mass spectrometry
- Author
- INGELS, Ann-Sofie M. E1 ; NEELS, Hugo2 3 ; LAMBERT, Willy E1 ; STOVE, Christophe P1
[1] Laboratory of Toxicology, Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium
[2] Laboratory of Toxicology, Antwerp University, Drie eiken Campus, 2000 Antwerp, Belgium
[3] Laboratory of Toxicology, ZNA Stuivenberg Hospital, Lange Beeldekensstraat 267, 2030 Antwerp, Belgium - Issue title
- MICROREACTIONS IN SEPARATION SCIENCE: REAGENTS AND TECHNIQUES
- Author (monograph)
- POOLE, C.F1
[1] Department of Chemistry, Wayne State University, Detroit, MI 48202, United States - Source
Journal of chromatography. 2013, Vol 1296, pp 84-92, 9 p ; ref : 34 ref
- CODEN
- JOCRAM
- ISSN
- 0021-9673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry; Pharmacology drugs; Pollution
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Biological matrices Gamma-hydroxybutyric acid (GHB) Gas chromatography coupled to mass Headspace-trap (HS-trap) In-vial derivatization Toxicology spectrometry (GC―MS)
- Keyword (fr)
- Analyse chimique Analyse quantitative Anesthésique Automatisation Chromatographie phase gazeuse Drogue récréative Dérivatisation Espace tête Estérification Homme Intoxication médicamenteuse Liquide biologique Malade Méthode couplée Méthylation Oxybate sodium Psychotrope Spectrométrie masse Sédatif Toxicologie Butyrique acide(4-hydroxy) GC MS
- Keyword (en)
- Chemical analysis Quantitative analysis Anesthetic Automation Gas chromatography Recreational drug Derivatization Headspace Esterification Human Drug intoxication Biological fluid Patient Coupled method Methylation Sodium oxybate Psychotropic Mass spectrometry Sedative Toxicology
- Keyword (es)
- Análisis químico Análisis cuantitativo Anestésico Automatización Cromatografía fase gaseosa Droga recreativa Derivatisación Espacio cabeza Esterificación Hombre Intoxicación medicamentosa Líquido biológico Enfermo Método acoplado Metilación Oxibato sódico Psicotropo Espectrometría masa Sedante Toxicología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02V Drug intoxications. Doping
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L06 Various organic compounds
- Discipline
- Drugs toxicity and drug intoxications General pharmacology Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27501388
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.chroma.2013.04.023 
https://dx.doi.org/10.1016/j.chroma.2013.04.023
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