The effect of carboxylesterase 1 (CES1) polymorphisms on the pharmacokinetics of oseltamivir in humans
- Author
- SUZAKI, Yuki1 ; UEMURA, Naoto3 ; TATEISHI, Masato6 ; OHASHI, Kyoichi1 2 4 ; TAKADA, Makoto6 ; OHYAMA, Tetsuji1 5 ; ITOHDA, Akiko4 ; MORIMOTO, Takuya1 2 ; IMAI, Hiromitsu1 2 4 ; HAMASAKI, Hajime2 4 ; INANO, Akihiro7 ; HOSOKAWA, Masakiyo8
[1] General Clinical Research Center, Oita University Hospital, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita 879-5593, Japan
[2] Clinical Pharmacology Center, Oita University Hospital, Hasama-machi, Yufu-shi, Oita, Japan
[3] Department of Pharmaceutical Medicine and Communication, Oita University Faculty of Medicine, Yufu-shi, Oita, Japan
[4] Department of Clinical Pharmacology & Therapeutics, Oita University Faculty of Medicine, Yufu-shi, Oita, Japan
[5] Department of Statistics, Oita University Faculty of Medicine, Yufu-shi, Oita, Japan
[6] Division of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan
[7] Clinical Research Center, Fukushima Medical University Hospital, Fukushima, Fukushima, Japan
[8] Laboratory of Drug Metabolism and Biopharmaceutics, Chiba Institute of Science, Choshi, Chiba, Japan - Source
European journal of clinical pharmacology. 2013, Vol 69, Num 1, pp 21-30, 10 p ; ref : 26 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- CES1 Carboxylesterase Genetic polymorphism Oseltamivir
- Keyword (fr)
- Adulte jeune Antiviral Carboxylesterase Génotype Oséltamivir Pharmacocinétique Pharmacogénétique Polymorphisme Variabilité génétique Carboxylic ester hydrolases Enzyme Esterases Exo-α-sialidase Glycosidases Glycosylases Génétique Homme Hydrolases Inhibiteur enzyme Inhibiteur neuraminidase
- Keyword (en)
- Young adult Antiviral Carboxylesterase Genotype Oseltamivir Pharmacokinetics Pharmacogenetics Polymorphism Genetic variability Carboxylic ester hydrolases Enzyme Esterases Exo-α-sialidase Glycosidases Glycosylases Genetics Human Hydrolases Enzyme inhibitor Neuraminidase inhibitor
- Keyword (es)
- Adulto joven Antiviral Carboxylesterase Genotipo Oseltamivir Farmacocinética Farmacogenética Polimorfismo Variabilidad genética Carboxylic ester hydrolases Enzima Esterases Exo-α-sialidase Glycosidases Glycosylases Genética Hombre Hydrolases Inhibidor enzima Inhibidor neuraminidas
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27579999
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00228-012-1315-5 
https://dx.doi.org/10.1007/s00228-012-1315-5
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