The Higher Diabetogenic Risk of Tacrolimus Depends on Pre-Existing Insulin Resistance. A Study in Obese and Lean Zucker Rats
- Author
- RODRIGUEZ-RODRIGUEZ, A. E1 ; TRINANES, J1 ; VELAZQUEZ-GARCIA, S2 ; PORRINI, E1 3 ; VEGA PRIETO, M. J4 ; DIEZ FUENTES, M. L4 ; AREVALO, M4 5 ; SALIDO RUIZ, E1 3 ; TORRES, A3 5
[1] Research Unit, University Hospital of the Canary Islands, Tenerife, Spain
[2] Department of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland
[3] Centre for Biomedical Research of the Canary Islands, University of La Laguna, Spain
[4] Central Laboratory, University Hospital of the Canary Islands, Tenerife, Spain
[5] Department of Human Anatomy and Histology, University of Salamanca, Salamanca, Spain - Source
American journal of transplantation (Print). 2013, Vol 13, Num 7, pp 1665-1675, 11 p ; ref : 44 ref
- ISSN
- 1600-6135
- Scientific domain
- Graft, transplantation
- Publisher
- Wiley, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Insulin resistance new-onset diabetes after transplantation tacrolimus
- Keyword (fr)
- Animal Antibactérien Diabète de type 1 Etat nutritionnel Facteur risque Homotransplantation Immunodépresseur Immunomodulateur Inhibiteur de la calcineurine Insuline Insulinorésistance Obésité Rat Risque Résistance tissu cible Stade précoce Tacrolimus Traitement Transplantation Chirurgie Endocrinopathie Greffe Hormone pancréatique Immunopathologie Inhibiteur synthèse protéique Lactone Macrolide Maladie autoimmune Maladie métabolique Mammalia Rodentia Trouble de la nutrition Vertebrata
- Keyword (en)
- Animal Antibacterial agent Type 1 diabetes Nutritional status Risk factor Homotransplantation Immunosuppressive agent Immunomodulator Calcineurin inhibitor Insulin Insulin resistance Obesity Rat Risk Target tissue resistance Early stage Tacrolimus Treatment Transplantation Surgery Endocrinopathy Graft Pancreatic hormone Immunopathology Protein synthesis inhibitor Lactone Macrolide Autoimmune disease Metabolic diseases Mammalia Rodentia Nutrition disorder Vertebrata
- Keyword (es)
- Animal Antibacteriano Diabetes de tipo 1 Estado nutricional Factor riesgo Homotrasplante Inmunodepresor Inmunomodulador Inhibidor calcineurina Insulina Resistancia insulina Obesidad Rata Riesgo Resistencia tejido blanco Estadio precoz Tacrolimús Tratamiento Trasplantación Cirugía Endocrinopatía Injerto Hormona pancreática Inmunopatología Inhibidor síntesis proteica Lactona Macrólido Enfermedad autoinmune Metabolismo patología Mammalia Rodentia Trastorno nutricíon Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B25 Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
- Discipline
- Endocrinopathies Metabolic diseases Surgery. Transplants, organs and tissues grafting. Graft pathologies
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27595778
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/ajt.12236 
https://dx.doi.org/10.1111/ajt.12236
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