The Role of Inherited TPMT and COMT Genetic Variation in Cisplatin-Induced Ototoxicity in Children With Cancer
- Author
- YANG, J. J1 ; LIM, J.Y. S1 2 ; ROBINSON, G. W6 ; EVANS, W. E1 ; PAPPO, A6 ; ZUO, J5 ; RELLING, M. V1 ; ONAR-THOMAS, A3 ; GAJJAR, A6 ; STEWART, C. F1 ; HUANG, J3 ; BASS, J4 ; WU, J3 ; WANG, C3 ; FANG, J5 ; STEWART, E6 ; HARSTEAD, E. H1 ; EWANS, W.E1
[1] Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States
[2] Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
[3] Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States
[4] Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, United States
[5] Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States
[6] Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States - Source
Clinical pharmacology and therapeutics. 2013, Vol 94, Num 2, pp 252-259, 8 p ; ref : 32 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Catechol O-methyltransferase Cisplatine Enfant Génotype Héréditaire Oreille Ototoxicité Polymorphisme Toxicité Tumeur maligne Variabilité génétique Agent alkylant Anticancéreux Cancer Enzyme Homme Methyltransferases Platine II Complexe Transferases
- Keyword (en)
- Catechol O-methyltransferase Cisplatin Child Genotype Hereditary Ear Ototoxicity Polymorphism Toxicity Malignant tumor Genetic variability Alkylating agent Antineoplastic agent Cancer Enzyme Human Methyltransferases Platinum II Complexes Transferases
- Keyword (es)
- Catechol O-methyltransferase Cisplatino Niño Genotipo Hereditario Oido Ototoxicidad Polimorfismo Toxicidad Tumor maligno Variabilidad genética Agente alquilante Anticanceroso Cáncer Enzima Hombre Methyltransferases Platino II Complejo Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Discipline
- General pharmacology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27614982
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/clpt.2013.121 
https://dx.doi.org/10.1038/clpt.2013.121
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