The DREAM Complex Mediates GIST Cell Quiescence and Is a Novel Therapeutic Target to Enhance Imatinib-Induced Apoptosis
- Author
- BOICHUK, Sergei1 8 ; PARRY, Joshua A1 ; SCHÖFFSKI, Patrick5 ; DEBIEC-RYCHTER, Maria6 ; DECAPRIO, James A3 ; DUENSING, Anette1 2 ; MAKIELSKI, Kathleen R1 ; LITOVCHICK, Larisa3 4 ; BARON, Julianne L1 ; ZEWE, James P1 ; WOZNIAK, Agnieszka5 ; MEHALEK, Keith R1 ; KORZENIEWSKI, Nina7 ; SENEVIRATNE, Danushka S1
[1] Cancer Virology Program, University of Pittsburgh Cancer Institute, Hillman Cancer Center, United States
[2] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
[3] Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States
[4] Department of Medicine, Virginia Commonwealth University, Richmond, Virginia, United States
[5] Department of Oncology and General Medical Oncology, KU Leuven and University Hospitals Leuven, Leuven, Belgium
[6] Department of Human Genetics, KU Leuven and University Hospitals Leuven, Leuven, Belgium
[7] Molecular Urooncology, Medical Faculty Heidelberg, University of Heidelberg School of Medicine, Heidelberg, Germany
[8] Department of Pathology, Kazan State Medical University, Kazan, Russian Federation - Source
Cancer research (Chicago, Ill.). 2013, Vol 73, Num 16, pp 5120-5129, 10 p ; ref : 42 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- Russian
- Keyword (fr)
- Anticancéreux Apoptose Ciblage Imatinib In vitro Mort cellulaire Quiescence Thérapeutique ciblée Traitement Tumeur stromale gastro-intestinale Cancer Enzyme Inhibiteur de la tyrosine kinase Inhibiteur enzyme Pathologie de l'appareil digestif Pathologie de l'estomac Pathologie de l'intestin Protein-tyrosine kinase Transferases Tumeur maligne
- Keyword (en)
- Antineoplastic agent Apoptosis Targeting Imatinib In vitro Cell death Quiescence Targeted therapy Treatment Gastrointestinal stromal tumor Cancer Enzyme Tyrosine kinase inhibitor Enzyme inhibitor Digestive diseases Gastric disease Intestinal disease Protein-tyrosine kinase Transferases Malignant tumor
- Keyword (es)
- Anticanceroso Apoptosis Blancado Imatinib In vitro Muerte celular Quietud Terapéutica dirigida Tratamiento Tumor estromal gastrointestinal Cáncer Enzima Inhibidor tyrosine kinase Inhibidor enzima Aparato digestivo patología Estómago patología Intestino patología Protein-tyrosine kinase Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27644093
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-13-0579 
https://dx.doi.org/10.1158/0008-5472.CAN-13-0579
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