The use of genetically modified mice in cancer risk assessment: Challenges and limitations
- Author
- EASTMOND, David A1 ; VULIMIRI, Suryanarayana V2 ; FRENCH, John E3 ; SONAWANE, Babasaheb2
[1] Department of Cell Biology & Neuroscience, University of California, Riverside, CA, United States
[2] National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC, United States
[3] Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States - Source
Critical reviews in toxicology. 2013, Vol 43, Num 8, pp 611-631, 21 p ; ref : 2 p.3/4
- ISSN
- 1040-8444
- Scientific domain
- Toxicology
- Publisher
- Informa Healthcare, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Carcinogen concordance dose-response hazard identification mechanism pathway-specificity study duration transgenic
- Keyword (fr)
- Animal transgénique Animal Article synthèse Cancer Carcinogène Concordance Identification Mécanisme action Relation dose réponse Souris Spécificité Test carcinogénicité Toxicité Tumeur maligne Evaluation du risque Mammalia Rodentia Vertebrata
- Keyword (en)
- Transgenic animal Animal Review Cancer Carcinogen Concordance Identification Mechanism of action Dose activity relation Mouse Specificity Carcinogenicity testing Toxicity Malignant tumor Risk evaluation Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal transgénico Animal Artículo síntesis Cáncer Carcinógeno Concordancia Identificación Mecanismo acción Relación dosis respuesta Ratón Especificidad Prueba carcinogenicidad Toxicidad Tumor maligno Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04E Carcinogenesis, carcinogens and anticarcinogens / 002B04E02 Chemical agents
- Discipline
- Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27727713
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.3109/10408444.2013.822844 
https://dx.doi.org/10.3109/10408444.2013.822844
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