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TGF-β/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1α expression

Author
ROZEN-ZVI, Benaya1 6 ; HAYASHIDA, Tomoko1 ; HUBCHAK, Susan C1 ; HANNA, Christian1 3 ; PLATANIAS, Leonidas C2 4 5 ; SCHNAPER, H. William1 3 4
[1] Division of Kidney Diseases, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
[2] Division of Hematology-Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
[3] Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, Illinois, United States
[4] Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States
[5] Department of Medicine, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, United States
[6] Department of Nephrology and Hypertension Rabin Medical Center, Petah-Tikva, Israel
Source

American journal of physiology. Renal physiology. 2013, Vol 74, Num 2 ; F485-F494 ; ref : 69 ref

ISSN
1931-857X
Scientific domain
Physiology, morphology; Urology, nephrology
Publisher
American Physiological Society, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Author keyword
HIF Smad3 TGF-β collagen fibrosis mTOR rapamycin
Keyword (fr)
Appareil urinaire Collagène Facteur croissance transformant β Fibrose Mammalia Sirolimus Inhibiteur mTOR Glycoprotéine Inhibiteur synthèse protéique Lactone Macrocycle Macrolide Vertebrata
Keyword (en)
Urinary system Collagen Transforming growth factor β Fibrosis Mammalia Sirolimus Glycoprotein Protein synthesis inhibitor Lactone Macrocycle Macrolide Vertebrata
Keyword (es)
Aparato urinario Colágeno Factor crecimiento transformante β Fibrosis Mammalia Sirolimús Glicoproteína Inhibidor síntesis proteica Lactona Macrociclo Macrólido Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A18 Vertebrates: urinary system

Discipline
Vertebrates : digestive and urinary system
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
27727943

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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