Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases
- Author
- SHIMIZU, T1 ; POMMIER, Y1
[1] Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, Building 37, Room 5C25, National Institutes of Health, Bethesda, MD 20892-4955, United States - Source
Leukemia. 1997, Vol 11, Num 8, pp 1238-1244 ; ref : 54 ref
- CODEN
- LEUKED
- ISSN
- 0887-6924
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aigu Alcaloïde Anticancéreux Apoptose Camptothécine Cysteine endopeptidases DNA topoisomerase Homme Inhibiteur enzyme Leucémie promyélocytaire Lignée cellulaire établie Mort cellulaire Serine endopeptidases Caspase Lignée HL60 Enzyme Hydrolases Hémopathie maligne Isomerases Peptidases
- Keyword (en)
- Acute Alkaloid Antineoplastic agent Apoptosis Cysteine endopeptidases DNA topoisomerase Human Enzyme inhibitor Promyelocytic leukemia Established cell line Cell death Serine endopeptidases HL60 cell line Enzyme Hydrolases Malignant hemopathy Isomerases Peptidases
- Keyword (es)
- Agudo Alcaloide Anticanceroso Apoptosis Cysteine endopeptidases DNA topoisomerase Hombre Inhibidor enzima Leucemia promielocítica Línea celular establecida Muerte celular Serine endopeptidases Enzima Hydrolases Hemopatía maligna Isomerases Peptidases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2780342
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.leu.2400734 
https://dx.doi.org/10.1038/sj.leu.2400734
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