The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers
- Author
- GOEY, Andrew K. L1 ; MEIJERMAN, Irma2 ; BEIJNEN, Jos H1 3 ; SCHELLENS, Jan H. M1 4
[1] Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, Netherlands
[2] Department of Pharmaceutical Sciences, Division of Pharmacology, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, Netherlands
[3] Department of Pharmacy & Pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, Netherlands
[4] Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands - Source
European journal of clinical pharmacology. 2013, Vol 69, Num 11, pp 1883-1890, 8 p ; ref : 40 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- CYP2D6 Clinical trial Dextromethorphan Grape seed extract Herb-drug interactions Pharmacokinetics
- Keyword (fr)
- Antitussif Cytochrome P450 Dextrométhorphane Essai clinique Graine Homme Individu sain Interaction médicamenteuse Isozyme Pharmacocinétique Cytochrome CYP2D6 Cytochrome P4502D6 Dérivé du morphinane Enzyme Opiacés Récepteur NMDA Récepteur glutamate
- Keyword (en)
- Antitussive agent Cytochrome P450 Dextromethorphan Clinical trial Seeds Human Healthy subject Drug interaction Isozyme Pharmacokinetics Cytochrome CYP2D6 Morphinan derivatives Enzyme Opiates NMDA receptor Glutamate receptor
- Keyword (es)
- Antitusivo Citocromo P450 Dextrometorfano Ensayo clínico Semillas Hombre Individuo sano Interacción medicamentosa Isozima Farmacocinética Morphinano derivado Enzima Opiados Receptor NMDA Receptor glutámato
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27822784
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00228-013-1558-9 
https://dx.doi.org/10.1007/s00228-013-1558-9
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