Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains
- Author
- SANDFORD, R1 ; SGOTTO, B1 ; HUGHES, J4 ; HARRIS, P4 ; APARICIO, S1 ; BRENNER, S1 ; VAUDIN, M2 ; WILSON, R. K2 ; CHISSOE, S2 ; PEPIN, K2 ; BATEMAN, A3 ; CHOTHIA, C3
[1] Department of Medicine, Addenbrooke's Hospital, Cambridge, CB2 2QQ, United Kingdom
[2] Genome Sequencing Centre, Washington University School of Medicine, St. Louis, MO 63108, United States
[3] MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom
[4] MRC Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, United Kingdom - Source
Human molecular genetics (Print). 1997, Vol 6, Num 9, pp 1483-1489 ; ref : 33 ref
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Evolution moléculaire Fonction cellulaire Glycoprotéine Génétique Homme Homologie Organisation gène Protéine membranaire Rein polykystique Structure domaine Séquence conservée Séquence nucléotide Fugu rubripes Polycystine Appareil urinaire pathologie Kyste Maladie héréditaire Pisces Rein pathologie Tumeur bénigne Vertebrata
- Keyword (en)
- Molecular evolution Cell function Glycoproteins Genetics Human Homology Gene organization Membrane protein Polycystic kidney Domain structure Conserved sequence Nucleotide sequence Urinary system disease Cyst Genetic disease Pisces Kidney disease Benign neoplasm Vertebrata
- Keyword (es)
- Evolución molecular Función celular Glicoproteina Genética Hombre Homología Organización gene Proteína membranar Riñón poliquístico Estructura dominio Secuencia conservada Secuencia nucleótido Aparato urinario patología Quiste Enfermedad hereditaria Pisces Riñón patología Tumor benigno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14C Malformations of the urinary system / 002B14C01 Kidneys
- Discipline
- Nephrology. Urinary tract diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2790391
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/hmg/6.9.1483 
https://dx.doi.org/10.1093/hmg/6.9.1483
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