Pharmacokinetic and pharmacodynamic study of Gefitinib in a mouse model of non-small-cell lung carcinoma with brain metastasis
- Author
- YAN CHEN1 ; MENGZHAO WANG1 ; WEI ZHONG1 ; JING ZHAO1
[1] The Respiratory Department of Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Peking 100730, China - Source
Lung cancer. 2013, Vol 82, Num 2, pp 313-318, 6 p ; ref : 27 ref
- CODEN
- LUCAE5
- ISSN
- 0169-5002
- Scientific domain
- Medical oncology; Pneumology
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Brain metastasis Cerebrospinal fluid Gefitinib Mouse model Non-small-cell lung carcinoma (NSCLC) Phosphorylated epidermal growth factor receptor (pEGFR)
- Keyword (fr)
- Activité biologique Cancer du poumon Carcinome non petite cellule bronchopulmonaire Carcinome non petite cellule Géfitinib Liquide céphalorachidien Modèle animal Pathologie de l'appareil respiratoire Pharmacocinétique Récepteur facteur croissance épiderme Souris Métastase cérébrale Cancer Mammalia Pathologie de l'encéphale Pathologie des bronches Pathologie des poumons Pathologie du système nerveux central Pathologie du système nerveux Rodentia Tumeur maligne Vertebrata
- Keyword (en)
- Biological activity Lung cancer non-small cell lung carcinoma Non small cell carcinoma Gefitinib Cerebrospinal fluid Animal model Respiratory disease Pharmacokinetics Epidermal growth factor receptor Mouse Cerebral metastasis Cancer Mammalia Cerebral disorder Bronchus disease Lung disease Central nervous system disease Nervous system diseases Rodentia Malignant tumor Vertebrata
- Keyword (es)
- Actividad biológica Cáncer del pulmón Carcinoma no pequeňa célula bronchopulmonar Carcinoma no pequeña célula Gefitinib Líquido cefalorraquídeo Modelo animal Aparato respiratorio patología Farmacocinética Receptor del factor de crecimiento epidérmico Ratón Metástasis cerebral Cáncer Mammalia Encéfalo patología Bronquio patología Pulmón patología Sistema nervosio central patología Sistema nervioso patología Rodentia Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses
- Discipline
- Neurology Pulmonology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27921841
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.lungcan.2013.08.013 
https://dx.doi.org/10.1016/j.lungcan.2013.08.013
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