Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response
- Author
- ZANNELLA, Vanessa E1 3 ; DAL PRA, Alan1 2 4 ; WOUTERS, Bradly G1 4 6 7 8 ; BRISTOW, Robert G1 2 3 4 ; KORITZINSKY, Marianne1 3 4 ; MUADDI, Hala1 5 ; MCKEE, Trevor D1 ; STAPLETON, Shawn1 6 ; SYKES, Jenna1 ; GLICKSMAN, Rachel2 4 ; CHAIB, Selim1 8 ; ZAMIARA, Paul1 3 ; MILOSEVIC, Michael1 2 3 4
[1] Princess Margaret Cancer Centre, University Health Network, Canada
[2] Radiation Medicine Program, University Health Network, Canada
[3] Institute of Medical Science, University of Toronto, Canada
[4] Department of Radiation Oncology, University of Toronto, Canada
[5] Faculty of Medicine, University of Toronto, Canada
[6] Department of Medical Biophysics, University of Toronto, Canada
[7] Selective Therapies Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada
[8] Department of Radiation Oncology (Maastro Lab), GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, Netherlands - Source
Clinical cancer research (Print). 2013, Vol 19, Num 24, pp 6741-6750, 10 p ; ref : 37 ref
- CODEN
- CCREF4
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Metformine Métabolisme Oxygénation Radiothérapie Traitement Tumeur maligne Reprogrammation cellulaire Biguanides Cancer Pharmacocinétique
- Keyword (en)
- Metformin Metabolism Oxygenation Radiotherapy Treatment Malignant tumor Cell reprogramming Biguanides Cancer Pharmacokinetics
- Keyword (es)
- Metformina Metabolismo Oxigenación Radioterapia Tratamiento Tumor maligno Biguanidas Cáncer Farmacocinética
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Discipline
- Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28044858
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1158/1078-0432.CCR-13-1787 
https://dx.doi.org/10.1158/1078-0432.CCR-13-1787
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1158\/1078-0432.CCR-13-1787\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Clinical cancer research (Print)\";s:9:\"\u0000*\u0000stitle\";s:25:\"Clin. cancer res. (Print)\";s:7:\"\u0000*\u0000date\";s:4:\"2013\";s:9:\"\u0000*\u0000volume\";s:2:\"19\";s:8:\"\u0000*\u0000issue\";s:2:\"24\";s:8:\"\u0000*\u0000spage\";s:4:\"6741\";s:8:\"\u0000*\u0000epage\";s:4:\"6750\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1078-0432\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:8:\"ZANNELLA\";s:10:\"\u0000*\u0000aufirst\";s:9:\"Vanessa E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:12:{i:0;s:13:\"DAL PRA, Alan\";i:1;s:17:\"WOUTERS, Bradly G\";i:2;s:17:\"BRISTOW, Robert G\";i:3;s:21:\"KORITZINSKY, Marianne\";i:4;s:12:\"MUADDI, Hala\";i:5;s:15:\"MCKEE, Trevor D\";i:6;s:16:\"STAPLETON, Shawn\";i:7;s:12:\"SYKES, Jenna\";i:8;s:17:\"GLICKSMAN, Rachel\";i:9;s:12:\"CHAIB, Selim\";i:10;s:13:\"ZAMIARA, Paul\";i:11;s:18:\"MILOSEVIC, Michael\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"CCREF4\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:8:\"\u0000*\u0000place\";s:16:\"Philadelphia, PA\";s:6:\"\u0000*\u0000pub\";s:40:\"American Association for Cancer Research\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1158\/1078-0432.CCR-13-1787\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Clinical cancer research (Print)\";s:9:\"\u0000*\u0000stitle\";s:25:\"Clin. cancer res. (Print)\";s:7:\"\u0000*\u0000date\";s:4:\"2013\";s:9:\"\u0000*\u0000volume\";s:2:\"19\";s:8:\"\u0000*\u0000issue\";s:2:\"24\";s:8:\"\u0000*\u0000spage\";s:4:\"6741\";s:8:\"\u0000*\u0000epage\";s:4:\"6750\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1078-0432\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:8:\"ZANNELLA\";s:10:\"\u0000*\u0000aufirst\";s:9:\"Vanessa E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:12:{i:0;s:13:\"DAL PRA, Alan\";i:1;s:17:\"WOUTERS, Bradly G\";i:2;s:17:\"BRISTOW, Robert G\";i:3;s:21:\"KORITZINSKY, Marianne\";i:4;s:12:\"MUADDI, Hala\";i:5;s:15:\"MCKEE, Trevor D\";i:6;s:16:\"STAPLETON, Shawn\";i:7;s:12:\"SYKES, Jenna\";i:8;s:17:\"GLICKSMAN, Rachel\";i:9;s:12:\"CHAIB, Selim\";i:10;s:13:\"ZAMIARA, Paul\";i:11;s:18:\"MILOSEVIC, Michael\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"CCREF4\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:8:\"\u0000*\u0000place\";s:16:\"Philadelphia, PA\";s:6:\"\u0000*\u0000pub\";s:40:\"American Association for Cancer Research\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:29:\"10.1158\/1078-0432.CCR-13-1787\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1158\/1078-0432.CCR-13-1787\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Clinical cancer research (Print)\";s:9:\"\u0000*\u0000stitle\";s:25:\"Clin. cancer res. (Print)\";s:7:\"\u0000*\u0000date\";s:4:\"2013\";s:9:\"\u0000*\u0000volume\";s:2:\"19\";s:8:\"\u0000*\u0000issue\";s:2:\"24\";s:8:\"\u0000*\u0000spage\";s:4:\"6741\";s:8:\"\u0000*\u0000epage\";s:4:\"6750\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1078-0432\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:8:\"ZANNELLA\";s:10:\"\u0000*\u0000aufirst\";s:9:\"Vanessa E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:12:{i:0;s:13:\"DAL PRA, Alan\";i:1;s:17:\"WOUTERS, Bradly G\";i:2;s:17:\"BRISTOW, Robert G\";i:3;s:21:\"KORITZINSKY, Marianne\";i:4;s:12:\"MUADDI, Hala\";i:5;s:15:\"MCKEE, Trevor D\";i:6;s:16:\"STAPLETON, Shawn\";i:7;s:12:\"SYKES, Jenna\";i:8;s:17:\"GLICKSMAN, Rachel\";i:9;s:12:\"CHAIB, Selim\";i:10;s:13:\"ZAMIARA, Paul\";i:11;s:18:\"MILOSEVIC, Michael\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"CCREF4\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:8:\"\u0000*\u0000place\";s:16:\"Philadelphia, PA\";s:6:\"\u0000*\u0000pub\";s:40:\"American Association for Cancer Research\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1158\/1078-0432.CCR-13-1787\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Clinical cancer research (Print)\";s:9:\"\u0000*\u0000stitle\";s:25:\"Clin. cancer res. (Print)\";s:7:\"\u0000*\u0000date\";s:4:\"2013\";s:9:\"\u0000*\u0000volume\";s:2:\"19\";s:8:\"\u0000*\u0000issue\";s:2:\"24\";s:8:\"\u0000*\u0000spage\";s:4:\"6741\";s:8:\"\u0000*\u0000epage\";s:4:\"6750\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1078-0432\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:8:\"ZANNELLA\";s:10:\"\u0000*\u0000aufirst\";s:9:\"Vanessa E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:12:{i:0;s:13:\"DAL PRA, Alan\";i:1;s:17:\"WOUTERS, Bradly G\";i:2;s:17:\"BRISTOW, Robert G\";i:3;s:21:\"KORITZINSKY, Marianne\";i:4;s:12:\"MUADDI, Hala\";i:5;s:15:\"MCKEE, Trevor D\";i:6;s:16:\"STAPLETON, Shawn\";i:7;s:12:\"SYKES, Jenna\";i:8;s:17:\"GLICKSMAN, Rachel\";i:9;s:12:\"CHAIB, Selim\";i:10;s:13:\"ZAMIARA, Paul\";i:11;s:18:\"MILOSEVIC, Michael\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"CCREF4\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:8:\"\u0000*\u0000place\";s:16:\"Philadelphia, PA\";s:6:\"\u0000*\u0000pub\";s:40:\"American Association for Cancer Research\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1158\/1078-0432.CCR-13-1787\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Clinical cancer research (Print)\";s:9:\"\u0000*\u0000stitle\";s:25:\"Clin. cancer res. (Print)\";s:7:\"\u0000*\u0000date\";s:4:\"2013\";s:9:\"\u0000*\u0000volume\";s:2:\"19\";s:8:\"\u0000*\u0000issue\";s:2:\"24\";s:8:\"\u0000*\u0000spage\";s:4:\"6741\";s:8:\"\u0000*\u0000epage\";s:4:\"6750\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1078-0432\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:8:\"ZANNELLA\";s:10:\"\u0000*\u0000aufirst\";s:9:\"Vanessa E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:12:{i:0;s:13:\"DAL PRA, Alan\";i:1;s:17:\"WOUTERS, Bradly G\";i:2;s:17:\"BRISTOW, Robert G\";i:3;s:21:\"KORITZINSKY, Marianne\";i:4;s:12:\"MUADDI, Hala\";i:5;s:15:\"MCKEE, Trevor D\";i:6;s:16:\"STAPLETON, Shawn\";i:7;s:12:\"SYKES, Jenna\";i:8;s:17:\"GLICKSMAN, Rachel\";i:9;s:12:\"CHAIB, Selim\";i:10;s:13:\"ZAMIARA, Paul\";i:11;s:18:\"MILOSEVIC, Michael\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"CCREF4\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response\";s:8:\"\u0000*\u0000place\";s:16:\"Philadelphia, PA\";s:6:\"\u0000*\u0000pub\";s:40:\"American Association for Cancer Research\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"10\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
