Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants

Author

DICHGANS, Martin^{1 2} ; MALIK, Rainer¹ ; O'DONNELL, Christopher J^{19 7} ; FORNAGE, Myriam²⁰ ; THORSTEINSDOTTIR, Unnur¹⁴ ; PSATY, Bruce M^{21 22 23} ; HENGSTENBERG, Christian; SESHADRI, Sudha¹⁹ ; ERDMANN, Jeanette⁴ ; BIS, Joshua C²⁴ ; PETERS, Annette; BONCORAGLIO, Giorgio B; KÖNIG, Inke R^{3 5} ; MÄRZ, Winfried; MESCHIA, James F; KATHIRESAN, Sekar⁹ ; IKRAM, M. Arfan; McPHERSON, Ruth; STEFANSSON, Kari¹⁴ ; SUDLOW, Cathie; REILLY, Muredach P; THOMPSON, John R; SHARMA, Pankaj; ROSAND, Jonathan^{6 8 9} ; HOPEWELL, Jemma C¹⁰ ; CHAMBERS, John C; WATKINS, Hugh¹¹ ; ROTHWELL, Peter M¹³ ; ROBERTS, Robert; MARKUS, Hugh S; SAMANI, Nilesh J; FARRALL, Martin^{11 12} ; SCHUNKERT, Heribert; CLARKE, Robert¹⁰ ; GRETARSDOTTIR, Solveig¹⁴ ; THORLEIFSSON, Gudmar¹⁴ ; MITCHELL, Braxton D¹⁵ ; ASSIMES, Themistocles L¹⁶ ; LEVI, Christopher^{17 18}
[1] Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany
[2] Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
[3] Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany
[4] Institut für integrative und experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany
[5] Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Germany
[6] Department of Neurology and Center for Human Genetic Research, Massachusetts General Hospital, Boston, United States
[7] Cardiology Division, Massachusetts General Hospital, Boston, United States
[8] Harvard Medical School, Boston, MA, United States
[9] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, United States
[10] Clinical Trial Service Unit and Epidemiological Studies Unit, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
[11] Wellcome Trust Centre for Human Genetics, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
[12] Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
[13] Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
[14] DeCODE Genetics, Reykjavik, Iceland
[15] Department of Medicine, University of Maryland School of Medicine, Baltimore, United States
[16] Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States
[17] Center for Translational Neuroscience and Mental Health Research, University of Newcastle, New South Wales, Australia
[18] Hunter Medical Research Institute, New South Wales, Australia
[19] National Heart, Lung and Blood Institute and NHLBI's Framingham Heart Study, MA, United States
[20] University of Texas Health Science Center at Houston, University of Washington, Seattle, United States
[21] Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, Seattle, United States
[22] Department of Medicine, University of Washington, Seattle, United States
[23] Department of Health Services, University of Washington, Seattle, United States
[24] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, United States
METASTROKE Consortium

Source

Stroke (1970). 2014, Vol 45, Num 1, pp 24-36, 13 p ; ref : 31 ref

CODEN

SJCCA7

ISSN

0039-2499

Scientific domain

Neurology

Publisher

Lippincott Williams & Wilkins, Hagerstown, MD

Publication country

United States

Document type

Article

Language

English

Author keyword

coronary artery disease genetics meta-analysis polymorphism, single nucleotide stroke

Keyword (fr)

Accident cérébrovasculaire Cardiopathie coronaire Ischémie de l'encéphale Pathologie cérébrovasculaire Pathologie du système nerveux Polymorphisme mononucléotide Ramollissement cérébral Pathologie de l'appareil circulatoire Pathologie de l'encéphale Pathologie des vaisseaux sanguins Pathologie du système nerveux central

Keyword (en)

Stroke Coronary heart disease Brain ischemia Cerebrovascular disease Nervous system diseases Single nucleotide polymorphism Cerebral infarction Cardiovascular disease Cerebral disorder Vascular disease Central nervous system disease

Keyword (es)

Accidente cerebrovascular Cardiopatía coronaria Isquemia encéfalo Vaso sanguíneo encéfalo patología Sistema nervioso patología Polimorfismo mononucleótido Infarto cerebral Aparato circulatorio patología Encéfalo patología Vaso sanguíneo patología Sistema nervosio central patología

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A03 Coronary heart disease

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A03 Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17C Vascular diseases and vascular malformations of the nervous system

Discipline

Cardiology. Circulatory system Neurology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

28126586

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS