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Conjugation of blocked ricin to an anti-CD19 monoclonal antibody increases antibody-induced cell calcium mobilization and CD19 internalization

Author
GOULET, A.-C; GOLDMACHER, V. S; LAMBERT, J. M; BARON, C; ROY, D.-C; KOUASSI, E
ImmunoGen, Inc, Cambridge, MA, United States
Maisonneuve-Rosemont Hospital Research Center, Montreal, Quebec, Canada
Source

Blood. 1997, Vol 90, Num 6, pp 2364-2375 ; ref : 54 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Anticorps monoclonal Calcium Homme Immunothérapie Immunotoxine In vitro Internalisation Lignée cellulaire établie Lymphocyte B Lymphome Ricin Transduction signal Antigène CD19 Hémopathie maligne Lymphoprolifératif syndrome
Keyword (en)
Monoclonal antibody Calcium Human Immunotherapy Immunotoxin In vitro Internalization Established cell line B-Lymphocyte Lymphoma Castor (seed) Signal transduction Malignant hemopathy Lymphoproliferative syndrome
Keyword (es)
Anticuerpo monoclonal Calcio Hombre Inmunoterapia Inmunotoxina In vitro Internalización Línea celular establecida Linfocito B Linfoma Ricino Transducción señal Hemopatía maligna Linfoproliferativo síndrome
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R03 Immunotherapy

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
2814217

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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