Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6
- Author
- UMAR, A1 ; KOI, M2 ; RISINGER, J. I2 ; GLAAB, W. E4 5 ; TINDALL, K. R4 5 ; KOLODNER, R. D6 ; BOLAND, C. R7 ; BARRETT, J. C2 3 ; KUNKEL, T. A1
[1] Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, United States
[2] Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, United States
[3] Curricula in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599, United States
[4] Laboratory of Environmental Carcinogenesis and Mutagenesis, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, United States
[5] Curricula in Toxicology, University of North Carolina, Chapel Hill, North Carolina 27599, United States
[6] Charles A. Dana Division of Human Cancer Genetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, United States
[7] Department of Medicine, University of California at San Diego, La Jolla, California 92093-0688, United States - Source
Cancer research (Baltimore). 1997, Vol 57, Num 18, pp 3949-3955 ; ref : 48 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agent alkylant Cellule tumorale Chromosome A2 DNA Guanidine(1-méthyl-2-nitro-1-nitroso) Gène Homme In vitro Instabilité Mutation Mécanisme Mésappariement base Réparation Résistance Réversibilité Transfert génétique Tumeur maligne Gène hMSH2 Gène hMSH6
- Keyword (en)
- Alkylating agent Tumor cell Chromosome A2 DNA Gene Human In vitro Instability Mutation Mechanism Base mismatching Repair Resistance Reversibility Genetic transfer Malignant tumor
- Keyword (es)
- Agente alquilante Célula tumoral Cromosoma A2 DNA Gen Hombre In vitro Inestabilidad Mutación Mecanismo Desapareamiento base Reparación Resistencia Reversibilidad Transferencia genética Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C07 Mutagenesis. Repair
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2829066
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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