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Second generation antimigraine 5-Ht1B/D agonists : Structure activity relationship and preclinical pharmacological distinctions

Author
YEVICH, J. P1 ; YOCCA, F. D1
[1] Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT. 06492, United States
Source

Current medicinal chemistry. 1997, Vol 4, Num 5, pp 295-312 ; ref : 87 ref

ISSN
0929-8673
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Bentham Science, Schiphol
Publication country
Netherlands
Document type
Article
Language
English
Keyword (fr)
Agoniste Animal Antimigraineux Article synthèse Composé aromatique Hétérocycle azote Hétérocycle oxygène Hétérocycle soufre In vitro In vivo Indole dérivé Long terme Mécanisme action Relation structure activité Récepteur sérotoninergique 5-HT1 Récepteur sérotoninergique 5-HT1B Récepteur sérotoninergique 5-HT1D
Keyword (en)
Agonist Animal Antimigrainous agent Review Aromatic compound Nitrogen heterocycle Oxygen heterocycle Sulfur heterocycle In vitro In vivo Indole derivatives Long term Mechanism of action Structure activity relation 5-HT1 receptor
Keyword (es)
Agonista Animal Agente antimigrañoso Artículo síntesis Compuesto aromático Heterociclo nitrógeno Heterociclo oxígeno Heterociclo azufre In vitro In vivo Indol derivado Largo plazo Mecanismo acción Relación estructura actividad Receptor serotoninérgico 5-HT1
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
2832139

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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