Hydrophobic Drug-Triggered Self-Assembly of Nanoparticles from Silk-Elastin-Like Protein Polymers for Drug Delivery
- Author
- XIA, Xiao-Xia1 ; MING WANG2 ; YINAN LIN2 ; QIAOBING XU2 ; KAPLAN, David L2
[1] State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dong-Chuan Road, Shanghai, 200240, China
[2] Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, Massachusetts 02155, United States - Source
Biomacromolecules. 2014, Vol 15, Num 3, pp 908-914, 7 p ; ref : 34 ref
- ISSN
- 1525-7797
- Scientific domain
- Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Agrégation moléculaire Cellule tumorale Composé biomimétique Cytotoxicité Distribution intracellulaire Doxorubicine Elastine Etude expérimentale In vitro Internalisation Libération Lignée HeLa Nanoencapsulation Nanoparticule Polymère vecteur Protéine recombinante Soie Solution aqueuse Vecteur médicament Propriété biologique
- Keyword (en)
- Biological activity Molecular aggregation Tumor cell Biomimetic compound Cytotoxicity Subcellular distribution Doxorubicin Elastin Experimental study In vitro Internalization Release Hela cell line Nanoencapsulation Nanoparticle Control release polymer Recombinant protein Silk Aqueous solution Drug carrier Biological properties
- Keyword (es)
- Actividad biológica Agregación molecular Célula tumoral Compuesto biomimético Citotoxicidad Doxorubicina Elastina Estudio experimental In vitro Internalización Liberación Célula HeLa Nanoencapsulación Nanopartícula Polímero vector Proteína recombinante Seda Solución acuosa Vector medicamento Propiedad biológica
- Classification
- Pascal
- 001 Exact sciences and technology / 001D Applied sciences / 001D09 Physicochemistry of polymers / 001D09C Natural polymers / 001D09C03 Proteins
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments Physical chemistry of polymers
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28363091
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/bm4017594 
https://dx.doi.org/10.1021/bm4017594
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