Protracted dosing of the lipophilic camptothecin analogue AR-67 in non-small cell lung cancer xenografts and humans
- Author
- TSAKALOZOU, Eleftheria1 ; ADANE, Eyob D1 ; YALI LIANG1 ; ARNOLD, Susanne M2 ; LEGGAS, Markos1
[1] Department of Pharmaceutical Sciences. College of Pharmacy, University of Kentucky. 789 S. Limestone St.. Room 323, Lexington, KY 40536, United States
[2] Division of Medical Oncology. Department of Internal Medicine. Markey Cancer Center. University of Kentucky. 800 Rose St., Lexington. KY 40536, United States - Source
Cancer chemotherapy and pharmacology. 2014, Vol 74, Num 1, pp 45-54, 10 p ; ref : 41 ref
- CODEN
- CCPHDZ
- ISSN
- 0344-5704
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Camptothecins Human pilot study Protracted dosing schedule Topoisomerase 1 Tumor pharmacokinetics
- Keyword (fr)
- Analogue Animal Anticancéreux Camptothécine Cancer du poumon Carcinome non petite cellule bronchopulmonaire Homme Hétérotransplantation Pharmacocinétique Posologie Traitement Tumeur maligne Topoisomérase Alcaloïde Cancer Chirurgie DNA topoisomerase Enzyme Greffe Inhibiteur de la topoisomérase I Inhibiteur enzyme Isomerases Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Transplantation
- Keyword (en)
- Analog Animal Antineoplastic agent Lung cancer non-small cell lung carcinoma Human Heterotransplantation Pharmacokinetics Posology Treatment Malignant tumor Alkaloid Cancer Surgery DNA topoisomerase Enzyme Graft Topoisomerase I inhibitor Enzyme inhibitor Isomerases Respiratory disease Bronchus disease Lung disease Transplantation
- Keyword (es)
- Análogo Animal Anticanceroso Cáncer del pulmón Carcinoma no pequeňa célula bronchopulmonar Hombre Heterotrasplante Farmacocinética Posología Tratamiento Tumor maligno Alcaloide Cáncer Cirugía DNA topoisomerase Enzima Injerto Inhibidor topoisomerase I Inhibidor enzima Isomerases Aparato respiratorio patología Bronquio patología Pulmón patología Trasplantación
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pharmacological treatments Pulmonology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28573038
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00280-014-2472-2 
https://dx.doi.org/10.1007/s00280-014-2472-2
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