The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients
- Author
- LUNDE, Ingrid1 ; BREMER, Sara2 ; MIDTVEDT, Karsten3 ; MOHEBI, Beata1 ; DAHL, Miriam1 ; BERGAN, Stein1 4 ; ASBERG, Anders1 3 ; CHRISTENSEN, Hege1
[1] Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Box 1068, Blindern, 0316 Oslo, Norway
[2] Department of Medical Biochemistry, Oslo University Hospital, Rikshospitalet, Oslo, Norway
[3] Department of Transplant Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
[4] Department of Pharmacology, Oslo University Hospital, Rikshospitalet, Oslo, Norway - Source
European journal of clinical pharmacology. 2014, Vol 70, Num 6, pp 685-693, 9 p ; ref : 33 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- CYP3A Calcineurin inhibitors Kidney recipients POR PPARA Pharmacokinetics
- Keyword (fr)
- Ciclosporine Cytochrome P450 Homme Immunodépresseur Immunomodulateur Inhibiteur de la calcineurine Isozyme Pharmacocinétique Receveur Rein Tacrolimus Traitement Transplantation Variant génétique Cytochrome P450 3A Appareil urinaire Chirurgie Enzyme Greffe Inhibiteur synthèse protéique Lactone Macrolide
- Keyword (en)
- Ciclosporin Cytochrome P450 Human Immunosuppressive agent Immunomodulator Calcineurin inhibitor Isozyme Pharmacokinetics Recipient Kidney Tacrolimus Treatment Transplantation Genetic variant Urinary system Surgery Enzyme Graft Protein synthesis inhibitor Lactone Macrolide
- Keyword (es)
- Ciclosporina Citocromo P450 Hombre Inmunodepresor Inmunomodulador Inhibidor calcineurina Isozima Farmacocinética Receptor Riñón Tacrolimús Tratamiento Trasplantación Variante genética Aparato urinario Cirugía Enzima Injerto Inhibidor síntesis proteica Lactona Macrólido
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28598543
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00228-014-1656-3 
https://dx.doi.org/10.1007/s00228-014-1656-3
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