A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes
- Author
- SHARMA, Sunita1 2 ; XIAOBO ZHOU1 2 ; VONAKIS, Becky M6 ; ADKINSON, N. Franklin6 ; AVILA, Lydiana7 ; SOTO-QUIROS, Manuel7 ; BARRAZA-VILLAREAL, Albino8 ; LEMANSKE, Robert F9 ; SOLWAY, Julian10 ; KRISHNAN, Jerry12 ; WHITE, Steven R10 ; CHEADLE, Chris6 ; THIBAULT, Derek M1 ; BERGER, Alan E6 ; JINSHUI FAN6 ; MEHER PREETHI BOORGULA6 ; NICOLAE, Dan11 ; GILLILAND, Frank13 ; BARNES, Kathleen6 ; LONDON, Stephanie J14 ; MARTINEZ, Fernando15 ; OBER, Carole11 ; CELEDON, Juan C16 ; HIMES, Blanca E1 ; CAREY, Vincent J1 ; WEISS, Scott T1 ; RABY, Benjamin A1 2 ; LIU, Andy3 ; SZEFLER, Stanley J3 ; STRUNK, Robert4 ; CASTRO, Mario4 ; HANSEL, Nadia N5 ; DIETTE, Gregory B5
[1] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, United States
[2] Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, United States
[3] Department of Pediatrics, National Jewish Health, Denver, United States
[4] Division of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, United States
[5] Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, United States
[6] Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, United States
[7] Hospital Nacional de Niños, San José, Costa Rica
[8] National Institute of Public Health of Mexico, Hospital Infantil de Mexico Federico Gomez, Mexico City, Montenegro
[9] Division of Allergy and Immunology, Department of Medicine, University of Wisconsin, Madison, United States
[10] Department of Pediatrics, University of Chicago, United States
[11] Department of Human Genetics, University of Chicago, United States
[12] Department of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, United States
[13] Division of Environmental and Occupational Health, Department of Medicine, University of Southern California, Los Angeles, United States
[14] National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, United States
[15] Arizona Respiratory Center, University of Arizona, Tucson, United States
[16] Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, United States - Source
Journal of allergy and clinical immunology. 2014, Vol 134, Num 5, pp 1153-1162, 10 p ; ref : 44 ref
- CODEN
- JACIBY
- ISSN
- 0091-6749
- Scientific domain
- Dermatology; Immunology, immunopathology, allergology; Pneumology
- Publisher
- Elsevier, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Asthma CD4+ lymphocytes expression quantitative trait locus haplotype integrative genomics regulatory variants
- Keyword (fr)
- Asthme Caractère quantitatif Enquête Gène Génome Génomique Génotype Génétique Haplotype Immunologie Immunopathologie Locus Lymphocyte T Surveillance Variabilité génétique Variant génétique Antigène CD4 Bronchopneumopathie obstructive Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons
- Keyword (en)
- Asthma Quantitative character Survey Gene Genome Genomics Genotype Genetics Haplotype Immunology Immunopathology Locus T-Lymphocyte Surveillance Genetic variability Genetic variant Obstructive pulmonary disease Respiratory disease Bronchus disease Lung disease
- Keyword (es)
- Asma Carácter cuantitativo Encuesta Gen Genoma Genómica Genotipo Genética Haplotipo Inmunología Inmunopatología Locus Linfocito T Vigilancia Variabilidad genética Variante genética Enfermedad pulmonar obstructiva Aparato respiratorio patología Bronquio patología Pulmón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B07 Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11B Chronic obstructive pulmonary disease, asthma
- Discipline
- Fundamental immunology Immunopathology Pulmonology Sarcoidosis. Granulomatosis of undetermined origin. Connective tissue diseases. Vasculitides
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28917288
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jaci.2014.04.011 
https://dx.doi.org/10.1016/j.jaci.2014.04.011
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arXiv access
