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A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes

Author
SHARMA, Sunita1 2 ; XIAOBO ZHOU1 2 ; VONAKIS, Becky M6 ; ADKINSON, N. Franklin6 ; AVILA, Lydiana7 ; SOTO-QUIROS, Manuel7 ; BARRAZA-VILLAREAL, Albino8 ; LEMANSKE, Robert F9 ; SOLWAY, Julian10 ; KRISHNAN, Jerry12 ; WHITE, Steven R10 ; CHEADLE, Chris6 ; THIBAULT, Derek M1 ; BERGER, Alan E6 ; JINSHUI FAN6 ; MEHER PREETHI BOORGULA6 ; NICOLAE, Dan11 ; GILLILAND, Frank13 ; BARNES, Kathleen6 ; LONDON, Stephanie J14 ; MARTINEZ, Fernando15 ; OBER, Carole11 ; CELEDON, Juan C16 ; HIMES, Blanca E1 ; CAREY, Vincent J1 ; WEISS, Scott T1 ; RABY, Benjamin A1 2 ; LIU, Andy3 ; SZEFLER, Stanley J3 ; STRUNK, Robert4 ; CASTRO, Mario4 ; HANSEL, Nadia N5 ; DIETTE, Gregory B5
[1] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, United States
[2] Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, United States
[3] Department of Pediatrics, National Jewish Health, Denver, United States
[4] Division of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, United States
[5] Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, United States
[6] Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, United States
[7] Hospital Nacional de Niños, San José, Costa Rica
[8] National Institute of Public Health of Mexico, Hospital Infantil de Mexico Federico Gomez, Mexico City, Montenegro
[9] Division of Allergy and Immunology, Department of Medicine, University of Wisconsin, Madison, United States
[10] Department of Pediatrics, University of Chicago, United States
[11] Department of Human Genetics, University of Chicago, United States
[12] Department of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, United States
[13] Division of Environmental and Occupational Health, Department of Medicine, University of Southern California, Los Angeles, United States
[14] National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, United States
[15] Arizona Respiratory Center, University of Arizona, Tucson, United States
[16] Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, United States
Source

Journal of allergy and clinical immunology. 2014, Vol 134, Num 5, pp 1153-1162, 10 p ; ref : 44 ref

CODEN
JACIBY
ISSN
0091-6749
Scientific domain
Dermatology; Immunology, immunopathology, allergology; Pneumology
Publisher
Elsevier, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
Asthma CD4+ lymphocytes expression quantitative trait locus haplotype integrative genomics regulatory variants
Keyword (fr)
Asthme Caractère quantitatif Enquête Gène Génome Génomique Génotype Génétique Haplotype Immunologie Immunopathologie Locus Lymphocyte T Surveillance Variabilité génétique Variant génétique Antigène CD4 Bronchopneumopathie obstructive Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons
Keyword (en)
Asthma Quantitative character Survey Gene Genome Genomics Genotype Genetics Haplotype Immunology Immunopathology Locus T-Lymphocyte Surveillance Genetic variability Genetic variant Obstructive pulmonary disease Respiratory disease Bronchus disease Lung disease
Keyword (es)
Asma Carácter cuantitativo Encuesta Gen Genoma Genómica Genotipo Genética Haplotipo Inmunología Inmunopatología Locus Linfocito T Vigilancia Variabilidad genética Variante genética Enfermedad pulmonar obstructiva Aparato respiratorio patología Bronquio patología Pulmón patología
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B07 Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11B Chronic obstructive pulmonary disease, asthma

Discipline
Fundamental immunology Immunopathology Pulmonology Sarcoidosis. Granulomatosis of undetermined origin. Connective tissue diseases. Vasculitides
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
28917288

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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