AMINO ACID SEQUENCE OF THE AHR1 LIGAND-BINDING DOMAIN PREDICTS AVIAN SENSITIVITY TO DIOXIN LIKE COMPOUNDS: IN VIVO VERIFICATION IN EUROPEAN STARLINGS

Author

ENG, Margaret L^{1 2} ; ELLIOTT, John E^{1 2} ; JONES, Stephanie P³ ; WILLIAMS, Tony D¹ ; DROUILLARD, Ken G⁴ ; KENNEDY, Sean W^{3 5}
[1] Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada
[2] Science and Technology Branch, Environment Canada, Pacific Wildlife Research Centre, Delta, British Columbia, Canada
[3] National Wildlife Research Centre, Environment Canada, Ottawa, Ontario, Canada
[4] Great Lakes Institute for Environmental Research, University of Windsor, Windsor, Ontario, Canada
[5] Centre for Advanced Research in Environmental Genomics Department of Biology, University of Ottawa, Ottawa, Ontario, Canada

Source

Environmental toxicology and chemistry. 2014, Vol 33, Num 12, pp 2753-2758, 6 p ; ref : 43 ref

CODEN

ETOCDK

ISSN

0730-7268

Scientific domain

Ecology; Environment; Pollution; Toxicology

Publisher

SETAC, Pensacola, FL

Publication country

United States

Document type

Article

Language

English

Author keyword

Aryl hydrocarbon receptor Birds Dioxin-like compounds Embryotoxicity Polychlorinated biphenyl

Keyword (fr)

Analyse structurale Carte peptidique Chlore Composé organique Cytochrome P450 Dibenzo-p-dioxine(2,3,7,8-tétrachloro) Dibenzo-p-dioxine(polychloro) Dibenzofurane(polychloro) Drug-metabolizing enzyme Embryon Fixation ligand Hydrocarbure chloré In vivo Isozyme Mortalité Polychlorobiphényles Prédiction Relation dose réponse Récepteur Ah Sensibilité Site fixation Structure primaire Sturnus vulgaris Séquence aminoacide Toxicité Tératogène Unspecific monooxygenase Cytochrome CYP1A4 Cytochrome CYP1A5 Embryotoxicité Sturnidae Aves Enzyme Oxidoreductases Polluant organique persistant Vertebrata

Keyword (en)

Structural analysis Peptide map Chlorine Organic compounds Cytochrome P450 Drug-metabolizing enzyme Embryo Ligand binding Chlorocarbon In vivo Isozyme Mortality Polychlorobiphenyls Prediction Dose activity relation Ah receptor Sensitivity Binding site Primary structure Sturnus vulgaris Aminoacid sequence Toxicity Teratogen Unspecific monooxygenase Aves Enzyme Oxidoreductases Persistent organic pollutant Vertebrata

Keyword (es)

Análisis estructural Mapa peptídico Cloro Compuesto orgánico Citocromo P450 Drug-metabolizing enzyme Embrión Fijación ligando Hidrocarburo clorado In vivo Isozima Mortalidad Polichlorobifenilos Predicción Relación dosis respuesta Receptor Ah Sensibilidad Sitio fijación Estructura primaria Sturnus vulgaris Secuencia aminoácido Toxicidad Teratogeno Unspecific monooxygenase Aves Enzima Oxidoreductases Contaminante organico persistente Vertebrata

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A30 Embryology: invertebrates and vertebrates. Teratology / 002A30E Teratology. Teratogens

Discipline

Embryology : invertebrates and vertebrates. Teratology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

28962336

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS