A global proteome approach in uric acid stimulated human aortic endothelial cells revealed regulation of multiple major cellular pathways
- Author
- OBERBACH, Andreas1 2 ; NEUHAUS, Jochen3 ; ADAMS, Volker8 ; JEHMLICH, Nico4 5 ; SCHLICHTING, Nadine6 ; HEINRICH, Marco1 ; KULLNICK, Yvonne1 ; MOHR, Friedrich-Wilhelm1 ; KUGLER, Joachim2 ; BAUMANN, Sven7 ; VÖLKER, Uwe4
[1] Department of Cardiac Surgery, Heart Center Leipzig, University of Leipzig, Leipzig, Germany
[2] Department of Health Sciences/Public Health, University of Dresden, Dresden, Germany
[3] Department of Urology, University of Leipzig, Leipzig, Germany
[4] Ernst-Moritz-Arndt-University Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, Germany
[5] Helmholtz Centre for Environmental Research, Department of Proteomics, Leipzig, Germany
[6] Department of Pediatric Surgery, University of Leipzig, Leipzig, Germany
[7] Helmholtz Centre for Environmental Research, Department of Metabolomics, Leipzig, Germany
[8] Department of Cardiology, University of Leipzig, Heart Center Leipzig, Leipzig, Germany - Source
International journal of cardiology. 2014, Vol 176, Num 3, pp 746-752, 7 p ; ref : 50 ref
- CODEN
- IJCDD5
- ISSN
- 0167-5273
- Scientific domain
- Cardiology, blood circulation, phlebology
- Publisher
- Elsevier, Shannon
- Publication country
- Ireland
- Document type
- Article
- Language
- English
- Author keyword
- Cardiovascular disease Eukaryotic initiation factor 4F (eIF4) Global proteome approach (2D-nano LC-MS/MS) Hypoxia-inducible factor 1-alpha (HIF-1α) Ubiquitin-proteasome pathway Uric acid
- Keyword (fr)
- Acide urique Aorte Cardiologie Cellule endothéliale Chromatographie phase liquide Facteur initiation Facteur transcription HIF1 Homme Hyperuricémie Multicatalytic endopeptidase complex Multiple Pathologie de l'appareil circulatoire Protéome Purine Régulation Spectrométrie masse tandem Ubiquitine Approche globale Maladie cardiovasculaire Appareil circulatoire Artère Enzyme Hydrolases Maladie métabolique Peptidases Vaisseau sanguin
- Keyword (en)
- Uric acid Aorta Cardiology Endothelial cell Liquid chromatography Initiation factor Transcription factor HIF1 Human Hyperuricemia Multicatalytic endopeptidase complex Multiple Cardiovascular disease Proteome Purine Regulation(control) Mass spectrometry MS/MS Ubiquitin Cardiovascular disease Circulatory system Artery Enzyme Hydrolases Metabolic diseases Peptidases Blood vessel
- Keyword (es)
- Urico ácido Aorta Cardiología Célula endotelial Cromatografía fase líquida Factor iniciación Factor transcripción HIF1 Hombre Hiperuricemia Multicatalytic endopeptidase complex Múltiple Aparato circulatorio patología Proteoma Purina Regulación Espectrometría masa en tándem Ubiquitina Cardiovascular enfermedad Aparato circulatorio Arteria Enzima Hydrolases Metabolismo patología Peptidases Vaso sanguíneo
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22E Other metabolic disorders / 002B22E01 Purines and pyrimidines (gout, hyperuricemia...)
- Discipline
- Cardiology. Circulatory system Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28962533
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ijcard.2014.07.102 
https://dx.doi.org/10.1016/j.ijcard.2014.07.102
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