A Physiologically Based Pharmacokinetic Model for Voriconazole Disposition Predicts Intestinal First-pass Metabolism in Children
- Author
- ZANE, Nicole R1 ; THAKKER, Dhiren R1
[1] Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy at The University of North Carolina at Chapel Hill, CB 7355, 100N Beard Hall, Chapel Hill, NC 27599, United States - Source
Clinical pharmacokinetics. 2014, Vol 53, Num 12, pp 1171-1182, 12 p ; ref : 45 ref
- CODEN
- CPKNDH
- ISSN
- 0312-5963
- Scientific domain
- Pharmacology drugs
- Publisher
- Adis International, Auckland
- Publication country
- New Zealand
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antifongique Effet premier passage Enfant Facteur prédictif Intestin Modèle PBPK Métabolisme Pharmacocinétique Voriconazole Appareil digestif Dérivé d'azole Dérivé du triazole Homme
- Keyword (en)
- Antifungal agent First pass effect Child Predictive factor Gut Physiologically based pharmacokinetic model Metabolism Pharmacokinetics Voriconazole Digestive system Azole derivatives Triazole derivatives Human
- Keyword (es)
- Antifúngico Efecto primer paso Niño Factor predictivo Intestino PBPK modelo Metabolismo Farmacocinética Voriconazol Aparato digestivo Azol derivado Triazol derivado Hombre
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S04 Antifungal agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 29009739
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s40262-014-0181-y 
https://dx.doi.org/10.1007/s40262-014-0181-y
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