Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- Author
- GENOVESE, Giulio1 2 4 ; KÄHLER, Anna K7 ; PURCELL, Shaun M13 ; SVANTESSON, Oscar7 ; LANDEN, Mikael10 ; HÖGLUND, Martin11 ; LEHMANN, Sören9 ; GABRIEL, Stacey B3 ; MORAN, Jennifer L1 ; LANDER, Eric S3 ; SULLIVAN, Patrick F14 7 ; SKLAR, Pamela13 ; HANDSAKER, Robert E1 2 4 ; GRÖNBERG, Henrik7 ; HULTMAN, Christina M7 ; McCARROLL, Steven A1 2 4 ; LINDBERG, Johan7 8 ; ROSE, Samuel A1 ; BAKHOUM, Samuel F12 ; CHAMBERT, Kimberly1 ; MICK, Eran5 ; NEALE, Benjamin M1 6 ; FROMER, Menachem13
[1] Stanley Center for Psychiatric Research, Cambridge, MA, United States
[2] Program in Medical and Population Genetics, Cambridge, MA, United States
[3] Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, MA, United States
[4] Department of Genetics, Harvard Medical School, Boston, United States
[5] Department of Systems Biology, Harvard Medical School, Boston, United States
[6] Analytic and Translational Genetics Unit and the Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, United States
[7] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden
[8] Science for Life Laboratory, Karolinska Institutet, Sweden
[9] Hematology Center and Center for Hematology and Regenerative Medicine, Karolinska University Hospital, Stockholm, Sweden
[10] Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
[11] Department of Medical Sciences and Division of Hematology, University Hospital, Uppsala, Sweden
[12] Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, United States
[13] Division of Psychiatric Genomics, Department of Psychiatry, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, United States
[14] Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, United States - Source
The New England journal of medicine. 2014, Vol 371, Num 26, pp 2477-2487, 11 p ; ref : 40 ref
- CODEN
- NEJMAG
- ISSN
- 0028-4793
- Scientific domain
- General medicine general surgery
- Publisher
- Massachusetts Medical Society, Waltham, MA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Facteur risque Hématopoïèse Médecine Sang Séquence nucléotide Tumeur maligne Cancer
- Keyword (en)
- Risk factor Hematopoiesis Medicine Blood Nucleotide sequence Malignant tumor Cancer
- Keyword (es)
- Factor riesgo Hematopoyesis Medicina Sangre Secuencia nucleótido Tumor maligno Cáncer
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H03 Cell differentiation, maturation, development, hematopoiesis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Discipline
- Generalities in medical sciences Molecular and cell biology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 29022660
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1056/NEJMoa1409405 
https://dx.doi.org/10.1056/NEJMoa1409405
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