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Supramolecular Glycodendrimer-Based Hybrid Drugs

Author
PAOLINO, Marco1 ; KOMBER, Hartmut2 ; MENNUNI, Laura3 ; CASELLI, Gianfranco3 ; APPELHANS, Dietmar2 ; VOIT, Brigitte2 ; CAPPELLI, Andrea1
[1] Dipartimento di Biotecnologie, Chimica e Farmacia and European Research Centre for Drug Discovery and Development, Università degli Studi di Siena, Via A. Moro 2, 53100 Siena, Italy
[2] Leibniz-Institut für Polymerforschung Dresden e.V., Hohe Strasse 6, 01069 Dresden, Germany
[3] Rottapharm Biotech S.r.l., Via Valosa di Sopra 3, 20900 Monza, Italy
Source

Biomacromolecules. 2014, Vol 15, Num 11, pp 3985-3993, 9 p ; ref : 52 ref

ISSN
1525-7797
Scientific domain
Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Antagoniste sérotonine Capacité fixation Cycloaddition dipolaire 1,3 Cyclodextrine Dendrimère Dioside Dérivé de la pipérazine Dérivé de la quinoléine Etude expérimentale Glycosylamine Groupe terminal Interaction intermoléculaire Modification chimique Polymère inclusion Polymère ramifié Polymère vecteur Promédicament Propèneimine polymère Préparation Récepteur sérotoninergique 5-HT3 Solution aqueuse Vecteur médicament Chimie clic Glycopolymère Groupe adamantyle Oside polymère Polymère aromatique
Keyword (en)
Serotonin antagonist Binding capacity 1,3-Dipolar cycloaddition Cyclodextrin Dendrimer Disaccharide Piperazine derivatives Quinoline derivatives Experimental study Glycosylamine End group Intermolecular interaction Chemical modification Inclusion polymer Branched polymer Control release polymer Prodrug Propyleneimine polymer Preparation 5-HT3 Serotonine receptor Aqueous solution Drug carrier Oside polymer Aromatic polymer
Keyword (es)
Antagonista serotonina Capacidad de fijación 1,3-Dipolar cicloadición Ciclodextrina Dendrímero Disacárido Piperazina derivado Quinolina derivado Estudio experimental Glicosilamina Grupo terminal Interacción intermolecular Modificación química Polímero inclusión Polímero ramificado Polímero vector Promedicamento Propenoimina polímero Preparación Receptor serotoninérgico 5-HT3 Solución acuosa Vector medicamento Osido polímero Polímero aromático
Classification
Pascal
001 Exact sciences and technology / 001D Applied sciences / 001D09 Physicochemistry of polymers / 001D09D Organic polymers / 001D09D03 Chemical reactions and properties / 001D09D03A Chemical modifications

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions

Discipline
General pharmacology Physical chemistry of polymers
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
29036878

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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