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Topical administration of dual siRNAs using fusogenic lipid nanoparticles for treating psoriatic-like plaques

Author
MAREPALLY, Srujan1 ; CEDAR HA BOAKYE1 ; PATEL, Apurva R1 ; GODUGU, Chandraiah1 ; DODDAPANENI, Ravi1 ; DESAI, Pinaki R2 ; SINGH, Mandip1
[1] College of Pharmacy & Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, United States
[2] Aveva Drug Delivery Systems, Miramar, FL 33025, United States
Source

Nanomedicine (London. Print). 2014, Vol 9, Num 14, pp 2157-2174, 18 p ; ref : 71 ref

ISSN
1743-5889
Scientific domain
Biomedical engineering; General medicine general surgery; Nanotechnologies, nanostructures, nanoobjects; Pharmacology drugs
Publisher
Future Medicine, London
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Lipofectamine™ RNAiMAX Psoriasis Area and Severity Index dual-fusogenic-nucleic acid lipid particles fusogenic-nucleic acid lipid particles imiquimod inflammation psoriasis siSTAT3 siTNF-α stratum corneum plus epidermis
Keyword (fr)
ARNsi Acide nucléique Facteur nécrose tumorale α Facteur transcription STAT3 Homme Imiquimod Immunomodulateur Interférence ARN Lipide Nanoparticule Psoriasis Silence expression génique Traitement Voie externe Nanomatériau Nanomédecine Cytokine Pathologie de la peau
Keyword (en)
siRNA Nucleic acids Tumor necrosis factor α Transcription factor STAT3 Man Imiquimod Immunomodulator RNA interference Lipids Nanoparticles Psoriasis Gene silencing Processing Topical administration Nanomedicine Cytokine Skin disease
Keyword (es)
ARNsi Factor necrosis tumoral α Factor transcripción STAT3 Imiquimod Inmunomodulador ARN interferencia Silencio expresión genética Vía externa Nanomedicina Citoquina Piel patología
Classification
Pascal
001 Exact sciences and technology / 001B Physics / 001B80 Cross-disciplinary physics: materials science; rheology / 001B80A Materials science / 001B80A07 Nanoscale materials and structures: fabrication and characterization

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02K Skin, nail, hair, dermoskeleton

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B08 Dermatology / 002B08D Psoriasis. Parapsoriasis. Lichen

Discipline
Dermatology Pharmacological treatments Physics and materials science
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
29041949

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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