Population characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapy
- Author
- ZHIHONG LU; RUIWEN ZHANG; DIASIO, R. B
Univ. Alabama Birmingham, dep. pharmacology toxicology, div. clin. pharmacology, Birmingham AL 35294-0019, United States - Source
Clinical pharmacology and therapeutics. 1995, Vol 58, Num 5, pp 512-522 ; ref : 31 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité enzymatique Analyse statistique Anticancéreux Dihydropyrimidine dehydrogenase (NADP+) Fluor Composé organique Fluorouracil Foie Homme Métabolisme Méthode immunoblotting Pyrimidine dérivé Tumeur maligne Enzyme Oxidoreductases
- Keyword (en)
- Enzymatic activity Statistical analysis Antineoplastic agent Dihydropyrimidine dehydrogenase (NADP+) Fluorine Organic compounds Liver Human Metabolism Immunoblotting assay Pyrimidine derivatives Malignant tumor Enzyme Oxidoreductases
- Keyword (es)
- Actividad enzimática Análisis estadístico Anticanceroso Dihydropyrimidine dehydrogenase (NADP+) Fluor Compuesto orgánico Hígado Hombre Metabolismo Pirimidina derivado Tumor maligno Enzima Oxidoreductases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2920064
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/0009-9236(95)90171-X 
https://dx.doi.org/10.1016/0009-9236(95)90171-X
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