Practical total synthesis of (2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol, the antitumorial and immunostimulatory α-galactosylceramide, KRN7000
- Author
- MORITA, M1 ; SAWA, E1 ; YAMAJI, K1 ; SAKAI, T1 ; NATORI, T1 ; KOEZUKA, Y1 ; FUKUSHIMA, H1 ; AKIMOTO, K1
[1] Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd. 3 Miyahara-cho, Takasaki-shi, Gunma 370-12, Japan - Source
Bioscience, biotechnology, and biochemistry. 1996, Vol 60, Num 2, pp 288-292 ; ref : 23 ref
- ISSN
- 0916-8451
- Scientific domain
- Biochemistry, molecular biology, biophysics; General biology; Biotechnology
- Publisher
- Japan Society for Bioscience Biotechnology and Agrochemistry, Tokyo
- Publication country
- Japan
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aldose Anticancéreux Céramide Glycolipide Glycoside Immunostimulant Sphingoglycolipide Synthèse chimique Synthèse totale Agélasphine analogue Galactopyranosyle(tétra-O-benzyl) bromure Hexacosanoïque acide KRN 7000 Lyxose Octadécane-3,4-diol(1-α-D-galactopyranosyloxy-2-hexacosanoylamino) Phosphonium(tridécyl triphényl) bromure
- Keyword (en)
- Aldose Antineoplastic agent Ceramide Glycolipid Glycoside Immunostimulant agent Sphingoglycolipid Chemical synthesis Total synthesis
- Keyword (es)
- Aldosa Anticanceroso Cerámida Glicolípido Glicósido Inmunoestimulante Esfingoglicolípido Síntesis química Síntesis total
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C09 Lipids
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Organic chemistry Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3046199
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1271/bbb.60.288 
https://dx.doi.org/10.1271/bbb.60.288
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