Preparation of phenolic paclitaxel metabolites
- Author
- PARK, H1 ; HEPPERLE, M1 ; BOGE, T. C1 ; HIMES, R. H; GEORG, G. I1
[1] Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66045, United States - Source
Journal of medicinal chemistry (Print). 1996, Vol 39, Num 14, pp 2705-2709 ; ref : 31 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Acylate Aminoacide Aminoalcool Anticancéreux Cellule tumorale Cytotoxicité Cétol Diterpène Hétérocycle oxygène In vitro Lignée cellulaire établie Mélanome B16 Métabolite Paclitaxel Phénols Polyol Synthèse chimique Azétidin-2-one(1-benzoyl-3-t-butyldiméthylsiloxy-4-[4-(t-butyldiméthylsiloxy)phényl]) Baccatine III(7-O-triéthylsilyl) Paclitaxel(2-O-débenzoyl-2-O-[3-hydroxybenzoyl]) Paclitaxel(3p-déphényl-3p-[4-hydroxyphényl]) Taxane dérivé Taxol dérivé
- Keyword (en)
- Biological activity Acylate Aminoacid Aminoalcohol Antineoplastic agent Tumor cell Cytotoxicity Ketol Diterpene Oxygen heterocycle In vitro Established cell line B16-Melanoma Metabolite Phenols Polyol Chemical synthesis
- Keyword (es)
- Actividad biológica Acilato Aminoácido Aminoalcohol Anticanceroso Célula tumoral Citotoxicidad Cetol Diterpeno Heterociclo oxígeno In vitro Línea celular establecida Melanoma B16 Metabolito Fenoles Poliol Síntesis química
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C05 Alicyclic compounds, terpenoids, prostaglandins, steroids / 001C03C05B Terpenoids
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Organic chemistry Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3131644
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm960142x 
https://dx.doi.org/10.1021/jm960142x
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