Potential antitumor agents. 24. Synthesis and pharmacological behavior of imidazo[2,1-b]thiazole guanylhydrazones bearing at least one chlorine
- Author
- ANDREANI, A1 ; RAMBALDI, M1 ; LEONI, A1 ; LOCATELLI, A1 ; BOSSA, R; FRACCARI, A; GALATULAS, I; SALVATORE, G
[1] Dipartimento di Scienze Farmaceutiche, Università di Bologna, Via Belmeloro 6, 40126 Bologna, Italy - Source
Journal of medicinal chemistry (Print). 1996, Vol 39, Num 14, pp 2852-2855 ; ref : 25 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Anticancéreux Benzène dérivé Cardiotonique Cellule tumorale Chimiothérapie Cobaye Coeur Composé bicyclique Cytotoxicité Guanidines Hétérocycle soufre azote In vitro In vivo Lignée HeLa Lignée cellulaire établie Pathologie expérimentale Relation structure activité Souris Synthèse chimique Traitement Tumeur Ehrlich Tumeur maligne Imidazo[2,1-b]thiazole-5-carbaldéhyde(6-aryl-2,3-dihydro) amidinohydrazone Imidazo[2,1-b]thiazole-5-carbaldéhyde(6-chloro-2,3-dihydro-2-méthyl) amidinohydrazone Imidazothiazole Chlore Composé organique Glande mammaire pathologie Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Antineoplastic agent Benzene derivatives Cardiotonic agent Tumor cell Chemotherapy Guinea pig Heart Bicyclic compound Cytotoxicity Guanidines Sulfur nitrogen heterocycle In vitro In vivo Hela cell line Established cell line Experimental disease Structure activity relation Mouse Chemical synthesis Treatment Ehrlich ascites tumor Malignant tumor Chlorine Organic compounds Mammary gland diseases Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Anticanceroso Benceno derivado Cardiotónico Célula tumoral Quimioterapia Cobayo Corazón Compuesto bicíclico Citotoxicidad Guanidinas Heterociclo azufre nitrógeno In vitro In vivo Célula HeLa Línea celular establecida Patología experimental Relación estructura actividad Ratón Síntesis química Tratamiento Tumor Ehrlich Tumor maligno Cloro Compuesto orgánico Glándula mamaria patología Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3134139
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm9509307 
https://dx.doi.org/10.1021/jm9509307
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