Amarogentin, a naturally occuring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani
- Author
- RAY, S1 ; MAJUMDER, H. K1 ; CHAKRAVARTY, A. K1 ; MUKHOPADHYAY, S1 ; GIL, R. R2 ; CORDELL, G. A2
[1] Indian Institute of Chemical Biology, Calcutta 700032, India
[2] Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States - Source
Journal of natural products (Print). 1996, Vol 59, Num 1, pp 27-29 ; ref : 40 ref
- CODEN
- JNPRDF
- ISSN
- 0163-3864
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
/
American Society of Pharmacognosy, Glendale, AZ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antiparasitaire Antiprotozoaire Biphényle dérivé DNA topoisomerase Glycoside In vitro Inhibiteur enzyme Iridoïde Isolement Lactone Leishmania donovani Mécanisme action Médecine traditionnelle Origine végétale Partie aérienne végétal Pharmacognosie Plante médicinale Amarogentine Amaroswerine Pyrano[3,4-c]pyran-2-one dérivé Pyranopyrane dérivé Sweroside Swertia chirata Inde Angiospermae Dicotyledones Enzyme Gentianaceae Isomerases Kinetoplastida Protozoa Spermatophyta Asie
- Keyword (en)
- Biological activity Parasiticid Antiprotozoal agent Biphenyl derivatives DNA topoisomerase Glycoside In vitro Enzyme inhibitor Iridoid Isolation Lactone Leishmania donovani Mechanism of action Folk medicine Plant origin Above ground plant part Pharmacognosy Medicinal plant India Angiospermae Dicotyledones Enzyme Gentianaceae Isomerases Kinetoplastida Protozoa Spermatophyta Asia
- Keyword (es)
- Actividad biológica Antiparasitario Antiprotozoario Bifenilo derivado DNA topoisomerase Glicósido In vitro Inhibidor enzima Iridoide Aislamiento Lactona Leishmania donovani Mecanismo acción Medicina tradicional Origen vegetal Parte aérea vegetal Farmacognosia Planta medicinal India Angiospermae Dicotyledones Enzima Gentianaceae Isomerases Kinetoplastida Protozoa Spermatophyta Asia
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3196702
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/np960018g 
https://dx.doi.org/10.1021/np960018g
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