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Prediction of furan pharmacokinetics from hepatocyte studies : Comparison of bioactivation and hepatic dosimetry in rats, mice, and humans

Author
KEDDERIS, G. L1 ; HELD, S. D1
[1] Chemical Industry Institute of Toxicology, P.O. Box 12137, Research Triangle Park, North Carolina 27709, United States
Source

Toxicology and applied pharmacology. 1996, Vol 140, Num 1, pp 124-130 ; ref : 38 ref

CODEN
TXAPA9
ISSN
0041-008X
Scientific domain
Pharmacology drugs; Toxicology
Publisher
Elsevier, San Diego, CA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activation métabolique Animal Comparaison interspécifique Composé volatil Foie Furane Homme Hépatocyte In vitro Métabolisme Rat Relation métabolisme toxicité Solvant Souris Toxicité Toxicocinétique Mammalia Rodentia Vertebrata
Keyword (en)
Metabolic activation Animal Interspecific comparison Volatile compound Liver Furan Human Hepatocyte In vitro Metabolism Rat Metabolism toxicity relation Solvent Mouse Toxicity Toxicokinetics Mammalia Rodentia Vertebrata
Keyword (es)
Activación metabólica Animal Comparación interespecífica Compuesto volátil Hígado Furano Hombre Hepatocito In vitro Metabolismo Rata Relación metabolismo toxicidad Solvente Ratón Toxicidad Toxicocinética Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L04 Solvents

Discipline
Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3209190

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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