Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I α 1 gene
- Author
- GRANT, S. F. A1 ; REID, D. M1 ; BLAKE, G2 ; HERD, R2 ; FOGELMAN, I2 ; RALSTON, S. H1
[1] Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen AB9 2ZD, United Kingdom
[2] Department of Nuclear Medicine, Guy's Hospital, London SE1 2RT, United Kingdom - Source
Nature genetics. 1996, Vol 14, Num 2, pp 203-205 ; ref : 29 ref
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Collagène Facteur risque Gène Génétique Homme Masse osseuse Os Ostéoporose Polymorphisme Promoteur transcription Prédisposition Site fixation Séquence régulatrice Facteur transcription Sp1 Glycoprotéine Maladie héréditaire Ostéopathie Système ostéoarticulaire pathologie
- Keyword (en)
- Collagen Risk factor Gene Genetics Human Bone mass Bone Osteoporosis Polymorphism Transcription promoter Predisposition Binding site Regulatory sequence Transcription factor Sp1 Glycoproteins Genetic disease Bone disease Diseases of the osteoarticular system
- Keyword (es)
- Colágeno Factor riesgo Gen Genética Hombre Masa oseosa Hueso Osteoporosis Polimorfismo Promotor transcripción Predisposición Sitio fijación Secuencia reguladora Glicoproteina Enfermedad hereditaria Osteopatía Sistema osteoarticular patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15H Malformations and congenital and or hereditary diseases involving bones. Joint deformations
- Discipline
- Osteoarticular pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3239000
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng1096-203 
https://dx.doi.org/10.1038/ng1096-203
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