Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer
- Author
- BURGER, A. M1 ; DOUBLE, J. A1 ; KONOPA, J2 ; BIBBY, M. C1
[1] Clinical Oncology Unit, University of Bradford, Bradford BD7 1DP, United Kingdom
[2] Department of Pharmaceutical Technology and Biochemistry, Technical University of Gdansk, Gdansk, Poland - Source
British journal of cancer. 1996, Vol 74, Num 9, pp 1369-1374 ; ref : 34 ref
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adénocarcinome Analogue Animal Anticancéreux Chimiothérapie Cytotoxicité Côlon DNA Essai préclinique In vitro Liaison Lignée cellulaire établie Modèle animal Rectum Souris Traitement C1310 C1311 Imidazo[4,5,1-ole]acridin-6-one(5-[2-(diéthylamino)éthylomino]-8-hydroxy) Imidazoacridine dérivé Appareil digestif pathologie Côlon pathologie Intestin pathologie Mammalia Rectum pathologie Rodentia Tumeur maligne Vertebrata
- Keyword (en)
- Adenocarcinoma Analog Animal Antineoplastic agent Chemotherapy Cytotoxicity Colon DNA Preclinical trial In vitro Binding Established cell line Animal model Rectum Mouse Treatment Digestive diseases Colonic disease Intestinal disease Mammalia Rectal disease Rodentia Malignant tumor Vertebrata
- Keyword (es)
- Adenocarcinoma Análogo Animal Anticanceroso Quimioterapia Citotoxicidad Colón DNA Ensayo preclínico In vitro Enlace Línea celular establecida Modelo animal Recto Ratón Tratamiento Aparato digestivo patología Colón patología Intestino patología Mammalia Recto patología Rodentia Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3255634
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/bjc.1996.551 
https://dx.doi.org/10.1038/bjc.1996.551
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