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Synthesis and 5-lipoxygenase inhibitory activities of some novel 2-substituted 5-benzofuran hydroxamic acids

Author
OHEMENG, K. A; APPOLINA, M. A; NGUYEN, V. N; SCHWENDER, C. F; SINGER, M; STEBER, M; ANSELL, J; ARGENTIERI, D; HAGEMAN, W
R.W. Johnson pharmaceutical res. inst., discovery res., Raritan NJ 08869, United States
Source

Journal of medicinal chemistry (Print). 1994, Vol 37, Num 21, pp 3663-3667 ; ref : 27 ref

CODEN
JMCMAR
ISSN
0022-2623
Scientific domain
Pharmacology drugs
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Acide hydroxamique Activité biologique Benzofurane dérivé Composé aromatique Composé bicyclique Hétérocycle oxygène In vitro In vivo Inhibiteur enzyme Lipoxygenase Souris Butyrique acide4-[N-hydroxy-N-(1-[2-(3,4,5-triméthoxyphényl)benzofur-5-yl]éthyl)carbamoyl] ester méthyle Furanecarbohydroxamique acide(N-[1-(2-phénylbenzofur-5-yl)éthyl]) Urée(1-hydroxy-1-[1-(2-phénylbenzofur-5-yl)éthyl]) Enzyme Mammalia Oxidoreductases Rodentia Vertebrata
Keyword (en)
Hydroxamic acid Biological activity Benzofuran derivatives Aromatic compound Bicyclic compound Oxygen heterocycle In vitro In vivo Enzyme inhibitor Lipoxygenase Mouse Enzyme Mammalia Oxidoreductases Rodentia Vertebrata
Keyword (es)
Acido hidroxámico Actividad biológica Compuesto aromático Compuesto bicíclico Heterociclo oxígeno In vitro In vivo Inhibidor enzima Lipoxygenase Ratón Enzima Mammalia Oxidoreductases Rodentia Vertebrata
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06A Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives

Discipline
Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3307494

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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