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Synthesis and cytotoxic evaluation of some styryl ketones and related compounds

Author
DIMMOCK, J. R1 ; KUMAR, P1 ; BATIST, G; BALZARINI, J; DE CLERCQ, E; QUAIL, J. W; PUGAZHENTHI, U; YANG, J; CHEN, M; REID, R. S; ALLEN, T. M; KAO, G. Y; COLE, S. P. C
[1] Univ. Saskatchewan, coll. pharmacy nutrition, Saskatoon SK, Canada
Source

European journal of medicinal chemistry. 1995, Vol 30, Num 3, pp 209-217 ; ref : 31 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Activité biologique Anticancéreux Azine Base Mannich Cellule tumorale Composé benzénique Composé conjugué Composé vinylique Cytotoxicité Cétone Diffraction RX Homme In vitro Lignée L1210 Lignée cellulaire établie Lymphocyte T Résistance Structure cristalline Synthèse chimique But-3-én-2-one azine(4,4p-diphényl) Pent-1-én-3-one(1-phényl-5-pipéridino) Pent-1-én-3-one(4-méthyl-1-phényl) Pyrazole(5-[4-chlorophényl]-1-[1-(4-chlorophényl)-4-méthyl-3-oxopentyl]-3-isopropyl)
Keyword (en)
Biological activity Antineoplastic agent Azine Mannich base Tumor cell Benzenic compound Conjugated compound Vinylic compound Cytotoxicity Ketone X ray diffraction Human In vitro L1210 cell line Established cell line T-Lymphocyte Resistance Crystalline structure Chemical synthesis
Keyword (es)
Actividad biológica Anticanceroso Azina Base Mannich Célula tumoral Compuesto bencénico Compuesto conjugado Compuesto vinílico Citotoxicidad Cetona Difracción RX Hombre In vitro Célula L1210 Línea celular establecida Linfocito T Resistencia Estructura cristalina Síntesis química
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3473893

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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