Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans
- Author
- LAVRIJSEN, K; VAN DYCK, D; VAN HOUDT, J; HENDRICKX, J; MONBALIU, J; WOESTENBORGHS, R; MEULDERMANS, W; HEYKANTS, J
Jannsen res. foundation, dep. drug metabolism pharmacokinetics, 2340 Beerse, Belgium - Source
Drug metabolism and disposition. 1995, Vol 23, Num 3, pp 354-362 ; ref : 32 ref
- CODEN
- DMDSAI
- ISSN
- 0090-9556
- Scientific domain
- Pharmacology drugs
- Publisher
- American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antidiarrhéique Homme Intestin Lopéramide Métabolisme Pharmacocinétique Promédicament Rat Relation métabolisme activité Réduction Lopéramide oxyde Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Antidiarrheal agent Human Gut Metabolism Pharmacokinetics Prodrug Rat Activity metabolism relation Reduction Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Antidiarreico Hombre Intestino Metabolismo Farmacocinética Promedicamento Rata Relación metabolismo actividad Reducción Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02H Digestive system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3480761
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0090-9556(25)06545-6 
https://dx.doi.org/10.1016/S0090-9556(25)06545-6
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