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Synthesis and properties of the monoesters of 5-fluorouridine with 4-carboxybutyric acid and their conjugates with chitosan

Author
ONISHI, H; MACHIDA, Y; NAGAI, T
Hoshi univ., fac. pharmaceutical sci., Shinagawa-ku, Tokyo 142, Japan
Source

Chemical and pharmaceutical bulletin. 1995, Vol 43, Num 2, pp 340-343 ; ref : 15 ref

CODEN
CPBTAL
ISSN
0009-2363
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Maruzen, Tokyo
Publication country
Japan
Document type
Article
Language
English
Keyword (fr)
Acylation Anticancéreux Antimétabolite Chitosane Composé conjugué Diacide carboxylique Effet milieu Hydrolyse In vitro Oside polymère Polymère vecteur Promédicament Pyrimidine nucléoside Ribonucléoside Synthèse chimique pH Glutarique acide anhydride Uridine(5-fluoro) Uridine(O-[4-carboxybutyryl]-5-fluoro) Vecteur médicament Fluor Composé organique
Keyword (en)
Acylation Antineoplastic agent Antimetabolic Chitosan Conjugated compound Dicarboxylic acid Medium effect Hydrolysis In vitro Oside polymer Control release polymer Prodrug Pyrimidine nucleoside Ribonucleoside Chemical synthesis pH Drug carrier Fluorine Organic compounds
Keyword (es)
Acilación Anticanceroso Antimetabólito Quitosano Compuesto conjugado Diácido carboxílico Efecto medio Hidrólisis In vitro Osido polímero Polímero vector Promedicamento Pirimidina nucleósido Ribonucleósido Síntesis química pH Fluor Compuesto orgánico
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3503967

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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