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Iterative protein structure-based drug design and synthesis of HIV protease inhibitors

Author
KALISH, V1 ; KALDOR, S; MUSICK, L1 ; BOR-WEN WU1 ; KEN SU; SHETTY, B1 ; TATLOCK, J1 ; DAVIES, J1 ; HAMMOND, M; DRESSMAN, B; FRITZ, J; APPELT, K1 ; REICH, S1
[1] Agouron Pharmaceuticals, San Diego CA 92121, United States
Conference title
International symposium on medicinal chemistry
Conference name
International symposium on medicinal chemistry (13 ; Paris 1994)
Author (monograph)
MULLER, Jean-Claude (Editor)
European Federation for Medicinal Chemistry, Europe (Funder/Sponsor)
American Chemical Society, Washington DC, United States (Funder/Sponsor)
International Union of Pure and Applied Chemistry, International (Funder/Sponsor)
Source

European journal of medicinal chemistry. 1995, Vol 30, pp 201s-214s ; SUP ; ref : 18 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Conference Paper
Language
English
Keyword (fr)
Animal Antiviral Biodisponibilité Hydroxysulfure organique Inhibiteur enzyme Isoquinoléine dérivé Modèle moléculaire Modélisation Phénols Proteinases Relation structure activité Structure cristalline Virus immunodéficience humaine Voie orale AG 1343 Benzoïque acide dérivé LY 289612 Enzyme Hydrolases Lentivirinae Retroviridae Virus
Keyword (en)
Animal Antiviral Bioavailability Organic hydroxysulfide Enzyme inhibitor Isoquinoline derivatives Molecular model Modeling Phenols Proteinases Structure activity relation Crystalline structure Human immunodeficiency virus Oral administration Enzyme Hydrolases Lentivirinae Retroviridae Virus
Keyword (es)
Animal Antiviral Biodisponibilidad Hidroxisulfuro orgánico Inhibidor enzima Isoquinoleína Modelo molecular Modelización Fenoles Proteinases Relación estructura actividad Estructura cristalina Human immunodeficiency virus Vía oral Enzima Hydrolases Lentivirinae Retroviridae Virus
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3567530

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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