Lethal α-thalassaemia created by gene targeting in mice and its genetic rescue
- Author
- PASZTY, C1 ; MOHANDAS, N1 ; STEVENS, M. E1 ; LORING, J. F; LIEBHABE, S. A; BRION, C. M1 ; RUBIN, E. M1
[1] Univ. California, human genome cent., Lawrence Berkeley lab., Berkeley CA 94720, United States - Source
Nature genetics. 1995, Vol 11, Num 1, pp 33-39 ; ref : 35 ref
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal transgénique Caractère létal Chaîne peptidique α Ciblage Délétion Globine Gène Génétique Modèle animal Mutation Restauration Souris Thalassémie α Anémie hémolytique Hémoglobinopathie Hémopathie Maladie héréditaire Mammalia Rodentia Vertebrata
- Keyword (en)
- Transgenic animal Lethal character Alpha-Peptide chain Targeting Deletion Globin Gene Genetics Animal model Mutation Restoration Mouse α-Thalassemia Hemolytic anemia Hemoglobinopathy Hemopathy Genetic disease Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal transgénico Carácter letal Cadena peptídica α Blancado Deleción Globina Gen Genética Modelo animal Mutación Restauración Ratón Talasemia α Anemia hemolítica Hemoglobinopatía Hemopatía Enfermedad hereditaria Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19A Diseases of red blood cells / 002B19A01 Anemias. Hemoglobinopathies
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3644447
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng0995-33 
https://dx.doi.org/10.1038/ng0995-33
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