Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin : potent agonists for 5-HT1D receptors
- Author
- PEREZ, M; FOURRIER, C; SIGOGNEAU, I; PAUWELS, P. J; PALMIER, C; JOHN, G. W; VALENTIN, J.-P; HALAZY, S
Cent. rech. Pierre Fabre, medicinal chemistry div., cellular molecular neurobiology lab. and cardiovascular diseases div., 81106 Castres, France - Source
Journal of medicinal chemistry (Print). 1995, Vol 38, Num 18, pp 3602-3607 ; ref : 20 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agoniste Animal Antimigraineux Carboxamide In vitro Indole dérivé Lapin Pipérazine dérivé Relation structure activité Récepteur sérotoninergique 5-HT1 Sulfonamide Synthèse chimique Caproïque acide(6-[3-(2-aminoéthyl)indol-5-yloxy])pipérazidide[4-(4-mésylamino)phényl] Indol-5-ol(3-[2-aminoéthyl]) Méthanesulfonique acide 4-pipérazinophénylamide Récepteur sérotoninergique 5-HT1Dα Lagomorpha Mammalia Vertebrata
- Keyword (en)
- Agonist Animal Antimigrainous agent Carboxamide In vitro Indole derivatives Rabbit Piperazine derivatives Structure activity relation 5-HT1 receptor Sulfonamide Chemical synthesis Lagomorpha Mammalia Vertebrata
- Keyword (es)
- Agonista Animal Agente antimigrañoso Carboxamida In vitro Indol derivado Conejo Relación estructura actividad Receptor serotoninérgico 5-HT1 Sulfonamida Síntesis química Lagomorpha Mammalia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3658932
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00018a020 
https://dx.doi.org/10.1021/jm00018a020
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