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Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin : potent agonists for 5-HT1D receptors

Author
PEREZ, M; FOURRIER, C; SIGOGNEAU, I; PAUWELS, P. J; PALMIER, C; JOHN, G. W; VALENTIN, J.-P; HALAZY, S
Cent. rech. Pierre Fabre, medicinal chemistry div., cellular molecular neurobiology lab. and cardiovascular diseases div., 81106 Castres, France
Source

Journal of medicinal chemistry (Print). 1995, Vol 38, Num 18, pp 3602-3607 ; ref : 20 ref

CODEN
JMCMAR
ISSN
0022-2623
Scientific domain
Pharmacology drugs
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Agoniste Animal Antimigraineux Carboxamide In vitro Indole dérivé Lapin Pipérazine dérivé Relation structure activité Récepteur sérotoninergique 5-HT1 Sulfonamide Synthèse chimique Caproïque acide(6-[3-(2-aminoéthyl)indol-5-yloxy])pipérazidide[4-(4-mésylamino)phényl] Indol-5-ol(3-[2-aminoéthyl]) Méthanesulfonique acide 4-pipérazinophénylamide Récepteur sérotoninergique 5-HT1Dα Lagomorpha Mammalia Vertebrata
Keyword (en)
Agonist Animal Antimigrainous agent Carboxamide In vitro Indole derivatives Rabbit Piperazine derivatives Structure activity relation 5-HT1 receptor Sulfonamide Chemical synthesis Lagomorpha Mammalia Vertebrata
Keyword (es)
Agonista Animal Agente antimigrañoso Carboxamida In vitro Indol derivado Conejo Relación estructura actividad Receptor serotoninérgico 5-HT1 Sulfonamida Síntesis química Lagomorpha Mammalia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3658932

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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