Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase
- Author
- VAN CALENBERGH, S1 ; VERLINDE, C. L. M. J; SOENENS, J1 ; DE BRUYN, A; CALLENS, M; BLATON, N. M; PEETERS, O. M; ROZENSKI, J; HOL, W. G. J; HERDEWIJN, P1
[1] Univ. Ghent, lab. medicinal chemistry, 9000 Ghent, Belgium - Source
Journal of medicinal chemistry (Print). 1995, Vol 38, Num 19, pp 3838-3849 ; ref : 21 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aminocyclitol Aminoglycoside Antiparasitaire Antiprotozoaire Glyceraldehyde-3-phosphate dehydrogenase (NADP+) Homme In vitro Inhibiteur enzyme Purine nucléoside Relation structure activité Synthèse chimique Trypanosoma brucei Adénosine(2p-désoxy-2p-[3-méthoxybenzamido]) Enzyme Oxidoreductases Protozoa Rhizoflagellata
- Keyword (en)
- Aminocyclitols Aminoglycoside Parasiticid Antiprotozoal agent Glyceraldehyde-3-phosphate dehydrogenase (NADP+) Human In vitro Enzyme inhibitor Purine nucleoside Structure activity relation Chemical synthesis Trypanosoma brucei Enzyme Oxidoreductases Protozoa Rhizoflagellata
- Keyword (es)
- Aminociclitol Aminoglicósido Antiparasitario Antiprotozoario Glyceraldehyde-3-phosphate dehydrogenase (NADP+) Hombre In vitro Inhibidor enzima Purina nucleósido Relación estructura actividad Síntesis química Trypanosoma brucei Enzima Oxidoreductases Protozoa Rhizoflagellata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3668292
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00019a014 
https://dx.doi.org/10.1021/jm00019a014
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