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Synthesis of 3-(2'-furoyl)indole derivatives as potential new ligands at the benzodiazepine receptor, structurally more restrained analogues of indoleglyoxylylamides

Author
DA SETTIMO, A1 ; PRIMOFIORE, G1 ; DA SETTIMO, F1 ; MARINI, A. M1 ; NOVELLINO, E; GRECO, G; MARTINI, C; SENATORE, G; LUCACCHINI, A
[1] Univ. Pisa, dip. sci. farmaceutiche, 56126 Pisa, Italy
Source

Il Farmaco (Pavia). 1995, Vol 50, Num 5, pp 311-320 ; ref : 33 ref

ISSN
0014-827X
Scientific domain
Pharmacology drugs
Publisher
Elsevier Science, Lausanne
Publication country
Switzerland
Document type
Article
Language
English
Keyword (fr)
Animal Composé aromatique Composé bicyclique Encombrement stérique Furane dérivé Hétérocycle azote Hétérocycle oxygène In vitro Modèle moléculaire Modèle électrostatique Modélisation Relation structure activité Récepteur benzodiazépinique Synthèse chimique Indole(3-[3-arylméthyl-2-furoyl]) Indole(3-[3-phényl-2-furoyl])
Keyword (en)
Animal Aromatic compound Bicyclic compound Steric hindrance Furan derivatives Nitrogen heterocycle Oxygen heterocycle In vitro Molecular model Electrostatic model Modeling Structure activity relation Benzodiazepine receptor Chemical synthesis
Keyword (es)
Animal Compuesto aromático Compuesto bicíclico Embarazo estérico Furano derivado Heterociclo nitrógeno Heterociclo oxígeno In vitro Modelo molecular Modelo electrostático Modelización Relación estructura actividad Receptor benzodiazepínico Síntesis química
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09D Gabaergic and benzodiazepinic system

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3708795

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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